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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/47171
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dc.creatorFabiano da Silveira Santospt_BR
dc.creatorCarolina Hahn da Silveirapt_BR
dc.creatorFábio Souza Nunespt_BR
dc.creatorDaniele Cristina Ferreirapt_BR
dc.creatorHenrique Fernandes Vieira Victóriapt_BR
dc.creatorKlaus Wilhelm Heinrich Krambrockpt_BR
dc.creatorOtávio Augusto Chavespt_BR
dc.creatorFabiano Severo Rodembuschpt_BR
dc.creatorBernardo Almeida Iglesiaspt_BR
dc.date.accessioned2022-11-11T13:15:26Z-
dc.date.available2022-11-11T13:15:26Z-
dc.date.issued2020-
dc.citation.volume49pt_BR
dc.citation.issue45pt_BR
dc.citation.spage16278pt_BR
dc.citation.epage16295pt_BR
dc.identifier.doihttps://doi.org/10.1039/d0dt01063dpt_BR
dc.identifier.issn14779234pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/47171-
dc.description.resumoNew isomeric tetra-cationic porphyrins containing peripheral [Pd(bpy)Cl]+ units attached to pyridyl substituents were synthesized and fully characterized. The porphyrins present an intense Soret band located in the blue spectral region and an additional four weaker red-shifted Q bands in the visible spectral region (about 500–700 nm). The obtained Strickler–Berg parameters indicate fully spin and symmetry allowed transitions for all the observed absorption bands. Both porphyrins present two fluorescence emission bands, an intense one located around 650 nm and an additional weak red-shifted emission at ∼710 nm. Fluorescence decay time profiles were obtained showing bi-exponential decay. The interaction of the porphyrins with bovine serum albumin (BSA) was studied in detail by a fluorescence quenching method and molecular docking analysis. In addition, the photodynamical activity of the porphyrins in the photooxidation of BSA was determined and compared with the light-induced formation of reactive oxygen species (ROS) by electron paramagnetic resonance (EPR) allied with the spin trapping method. The results show that the Pd(II)-bypyridyl tetra-cationic porphyrins are promising candidates for the photooxidation of biological substrates used in photodynamic therapy (PDT).pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE FÍSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofDalton Transactionspt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectBSA interactionspt_BR
dc.subjectIsomeric tetra-cationic porphyrinspt_BR
dc.subject.otherPorphyrinspt_BR
dc.titlePhotophysical, photodynamical, redox properties and BSA interactions of novel isomeric tetracationic peripheral palladium(II)-bipyridyl porphyrinspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://pubs.rsc.org/en/content/articlelanding/2020/DT/D0DT01063Dpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4130-2083pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4289-7368pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5988-6016pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9523-1298pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4846-2189pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7562-0285pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6211-7659pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6528-2318pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4039-6316pt_BR
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