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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/47499
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dc.creatorJéssica Galbiati Barbosapt_BR
dc.creatorFrancine Benettipt_BR
dc.creatorMarjorie de Oliveira Gallinaript_BR
dc.creatorMarina Carminattipt_BR
dc.creatorAnna Beatriz Dias da Silvapt_BR
dc.creatorIsabela Nakahara Ikeda Lopespt_BR
dc.creatorAndré Luiz Fraga Brisopt_BR
dc.creatorLuciano Tavares Ângelo Cintrapt_BR
dc.date.accessioned2022-11-28T13:22:36Z-
dc.date.available2022-11-28T13:22:36Z-
dc.date.issued2019-07-13-
dc.citation.volume24pt_BR
dc.citation.issue3pt_BR
dc.citation.spage1299pt_BR
dc.citation.epage1309pt_BR
dc.identifier.doihttps://doi.org/10.1007/s00784-019-03009-5pt_BR
dc.identifier.issn14326981pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/47499-
dc.description.resumoObjectives: MI Paste Plus remineralizer (Rem) strengthens dental structures after bleaching. We investigated the effect of Rem on the penetration of hydrogen peroxide (H2O2), bleaching effectiveness, and pulp inflammation after bleaching. Materials and methods: Bovine disks were grouped as follows (n = 10): control (untreated), bleached (Ble; 35% H2O2, 30 min), Ble-Rem (H2O2 followed by Rem, 30 min), Rem-Ble (Rem followed by H2O2), Rem-Ble-Rem (Rem before and after H2O2), and Ble+Rem (mixture of Rem with H2O2, 1:1, 30 min). The penetration of H2O2 was quantified and bleaching efficacy was analyzed. Upper rat molars (n = 10) received the same treatments at random. The rats were euthanized after two days and 30 days, and their jaws were removed for histological analysis. Statistical tests were performed (P < 0.05). Results: The bleached groups, except Ble+Rem (P > 0.05), showed significant H2O2 penetration compared with control (P < 0.05). Color alteration analysis showed that ΔL and ΔE were significantly higher in the bleached groups than those in control (P < 0.05); the Δb of the bleached groups differed from that of control at 24 h (P < 0.05). At two days, necrosis or inflammation was observed in the bleached groups compared with control (P < 0.05), except Ble+Rem, which was similar to control (P > 0.05). At 30 days, tertiary dentin formation was significant in the bleached groups (P < 0.05), except Ble+Rem (P > 0.05). Conclusion: The mixture of MI Paste Plus and bleaching gel reduces H2O2 penetration and pulp damage and maintains bleaching effectiveness. Clinical relevance: Because bleaching can damage dental tissues, we studied a new bleaching protocol that reduces damage to the pulp tissue while maintaining bleaching efficiency: a single application of 30 min of MI Paste Plus mixed with 35% H2O2 bleaching gel (1:1)pt_BR
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulopt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofClinical Oral Investigationspt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectCasein phosphopeptide-amorphous calcium phosphate (CPP-ACP);pt_BR
dc.subjectDental bleachingpt_BR
dc.subjectHydrogen peroxidept_BR
dc.subjectMI Paste Pluspt_BR
dc.subjectPulp inflammationpt_BR
dc.subject.otherTooth bleachingpt_BR
dc.subject.otherHydrogen peroxidept_BR
dc.subject.otherMolarpt_BR
dc.subject.otherDentinpt_BR
dc.titleBleaching gel mixed with MI paste plus reduces penetration of H2O2 and damage to pulp tissue and maintains bleaching effectivenesspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s00784-019-03009-5pt_BR
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