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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/47551
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dc.creatorMarina Carminattipt_BR
dc.creatorFrancine Benettipt_BR
dc.creatorRenato Luiz Siqueirapt_BR
dc.creatorEdgar Dutra Zanottopt_BR
dc.creatorAndré Luiz Fraga Brisopt_BR
dc.creatorAntônio Hernandes Chaves-Netopt_BR
dc.creatorLuciano Tavares Ângelo Cintrapt_BR
dc.date.accessioned2022-11-29T21:34:22Z-
dc.date.available2022-11-29T21:34:22Z-
dc.date.issued2020-06-08-
dc.citation.volume28pt_BR
dc.citation.spage01pt_BR
dc.citation.epage10pt_BR
dc.identifier.doihttps://doi.org/10.1590/1678-7757-2019-0384pt_BR
dc.identifier.issn16787765pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/47551-
dc.description.resumoObjectives This study evaluated if the use of a bioactive glass-ceramic-based gel, named Biosilicate (BS), before, after or mixed with bleaching gel, could influence the inflammation of the dental pulp tissue of rats’ molars undergoing dental bleaching with hydrogen peroxide (H2O2). Methodology The upper molars of Wistar rats (Rattus norvegicus, albinus) were divided into Ble: bleached (35% H2O2, 30-min); Ble-BS: bleached and followed by BS-based gel application (20 min); BS-Ble: BS-based gel application and then bleaching; BS/7d-Ble: BS-based gel applications for 7 days and then bleaching; Ble+BS: blend of H2O2 with BS-based gel (1:1, 30-min); and control: placebo gel. After 2 and 30 days (n=10), the rats were euthanized for histological evaluation. The Kruskal-Wallis and Dunn statistical tests were performed (P<0.05). Results At 2 days, the Ble and Ble-BS groups had significant alterations in the pulp tissue, with an area of necrosis. The groups with the application of BS-based gel before H2O2 had moderate inflammation and partial disorganization in the occlusal third of the coronary pulp and were significantly different from the Ble in the middle and cervical thirds (P<0.05). The most favorable results were observed in the Ble+BS, which was similar to the control in all thirds of the coronary pulp (P>0.05). At 30 days, the pulp tissue was organized and the bleached groups presented tertiary dentin deposition. The Ble group had the highest deposition of tertiary dentin, followed by the Ble-BS, and both were different from control (P<0.05). Conclusion A single BS-based gel application beforehand or BS-based gel blended with a bleaching gel minimize the pulp damage induced by dental bleaching.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulopt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Applied Oral Sciencept_BR
dc.rightsAcesso Abertopt_BR
dc.subjectBioactive glasspt_BR
dc.subjectDental pulppt_BR
dc.subjectHydrogen peroxidept_BR
dc.subjectTooth bleaching.pt_BR
dc.subjectTooth remineralizationpt_BR
dc.subject.otherDental pulppt_BR
dc.subject.otherHydrogen peroxidept_BR
dc.subject.otherTooth bleachingpt_BR
dc.subject.otherTooth remineralizationpt_BR
dc.titleExperimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in ratspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.scielo.br/j/jaos/a/rWmYM9cjZDtHyVFpBKNKDyf/?lang=enpt_BR
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