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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/47845
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dc.creatorThallyta Maria Vieirapt_BR
dc.creatorLeydiana Duarte Fonsecapt_BR
dc.creatorGabriela Almeida Bastospt_BR
dc.creatorViviane de Oliveira Vasconcelospt_BR
dc.creatorMaria Luiza França Silvapt_BR
dc.creatorFranciellen Morais Costapt_BR
dc.creatorAdriano Vinicius de Paiva Ferreirapt_BR
dc.creatorNeide Judith Faria de Oliveirapt_BR
dc.creatorEduardo Robson Duartept_BR
dc.date.accessioned2022-12-08T15:17:48Z-
dc.date.available2022-12-08T15:17:48Z-
dc.date.issued2017-01-31-
dc.citation.volume41pt_BR
dc.citation.spage99pt_BR
dc.citation.epage106pt_BR
dc.identifier.doi10.1007/s11259-017-9677-xpt_BR
dc.identifier.issn1573-7446pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/47845-
dc.description.resumoObjective: this study evaluated the effects in vitro and in vivo of Agaricus blazei against Haemonchus contortus in sheep. Methods: the in vitro efficacy of aqueous extract on egg hatching inhibition (EHI) was investigated and after 72 h incubation with varying concentrations the effects on, blastomeres, embryonated eggs, and first stage larvae (L1) were evaluated. Larval development inhibition (LDI) for dry powder and the aqueous extract were evaluated in fecal cultures of sheep infected with H. contortus. In vivo efficacy was determined by reduction in fecal egg count (FEC). Lambs were treated with powder A. blazei (11.4 g/kg pc) or trichlorfon, or were untreated and the possible toxicity of this fungus was monitored by plasmatic enzyme analysis. Results: concentrations equal to and higher than 3.62 mg/mL and of aqueous extract were 100% effective in the EHI test. In the LDI test, LC90 was estimated for 5.66 and 106.0 mg/g fecal culture for aqueous extract and powder, respectively. The mean FEC in lambs 14 days post-treatment with A. blazei powder was significantly lower than observed for the negative control, and the serum levels of aspartate transaminase and alanine transaminase were normal. Conclusion: the fungi supplementation promotes, respectively, high and moderate anthelmintic efficacy with in vitro and in vivo tests, respectively, suggesting it as an alternative or complementary treatment for haemonchosis in sheep.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofVeterinary Research Communicationspt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherHaemonchus contortuspt_BR
dc.subject.otherBasidiomicetospt_BR
dc.subject.otherOvinos - Doençaspt_BR
dc.titleControl of Haemonchus contortus in sheep using basidiocarps of Agaricus blazei Murrilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s11259-017-9677-xpt_BR
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