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Type:	Artigo de Periódico
Title:	Mortality predictors after liver transplant in the intensive care unit
Authors:	Ana Paula Ragonete Dos Anjos Agostini Ilka de Fátima Santana Ferreira Boin Rodrigo Marques Tonella Aline Maria Heidemann Santos Antonio Luis Eiras Falcão Claudinéia Muterle Logato Lígia dos Santos Roceto Ratti Luciana Castilho de Figueiredo Luíz Cláudio Martins
Abstract:	Background: The goal of this study was to evaluate the predictive factors of mortality in patients after liver transplantation in an intensive care unit from the University Hospital. Methods: This observational study was conducted by using a database analysis of University Hospital. The sample consisted of patients after liver transplantation registered in the database. The study variables of Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Disease Classification II (APACHE II), Model for End-Stage Liver Disease, and Child-Pugh scores, and the days of hospitalization in intensive care unit, mechanical ventilation time, and reintubation rate, were correlated. Statistical analysis was performed by using the χ2 test or Fisher exact test, the Mann-Whitney test, and logistic regression analysis. Results: Fifty-eight individuals were analyzed. In the death group, the days of hospitalization in the intensive care unit were within 12 ± 14 days, the time of mechanical ventilation was 180 ± 148 hours, the APACHE II value was 17.6 ± 7.3, the Sequential Organ Failure Assessment score was 8.2 ± 2.7, and reintubation was 40%. In the multivariate regression, the predictive indexes of mortality were the mortality given by APACHE II (odds ratio, 1.1; CI, 1.03–1.17; P = .004), mechanical ventilation time (odds ratio, 1.02; CI, 1.01–1.04; P = .001), and reintubation (odds ratio, 9.06; CI, 1.83–44.9; P = .007). An increase of 1 unit in APACHE II mortality increases the risk of death by 10.2%, and each hour of mechanical ventilation increases the risk of death by 2.6%. Conclusions: The time of mechanical ventilation, orotracheal reintubation, and the mortality given by APACHE II were the variables that best predicted death in this study.
Subject:	Transplante de fígado Transplante de fígado / mortalidade Unidade de terapia intensiva
language:	eng
metadata.dc.publisher.country:	Brasil
Publisher:	Universidade Federal de Minas Gerais
Publisher Initials:	UFMG
metadata.dc.publisher.department:	EEF - DEPARTAMENTO DE FISIOTERAPIA
Rights:	Acesso Aberto
metadata.dc.identifier.doi:	https://doi.org/10.1016/j.transproceed.2018.02.087
URI:	http://hdl.handle.net/1843/48591
Issue Date:	Jun-2018
metadata.dc.url.externa:	https://www.sciencedirect.com/science/article/pii/S0041134518302549?via%3Dihub
metadata.dc.relation.ispartof:	Transplantation Proceedings
Appears in Collections:	Artigo de Periódico

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