Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/48808
Type: Artigo de Periódico
Title: Twin studies for the prognosis, prevention and treatment of musculoskeletal conditions
Authors: Lucas Calais Ferreira
Vinícius Cunha Oliveira
Jeffrey Mark Craig
Louisa Flander
John Llewelyn Hopper
Luci Fuscaldi Teixeira-Salmela
Paulo Henrique Ferreira
Abstract: Background: Musculoskeletal conditions are highly prevalent in our ageing society and are therefore incurring substantial increases in population levels of years lived with disability (YLD). An evidence-based approach to the prognosis, prevention, and treatment of those disorders can allow an overall improvement in the quality of life of patients, while also softening the burden on national health care systems. Methods: In this Masterclass article, we provide an overview of the most relevant twin study designs, their advantages, limitations and major contributions to the investigation of traits related to the domain of musculoskeletal physical therapy. Conclusions: Twin studies can be an important scientific tool to address issues related to musculoskeletal conditions. They allow researchers to understand how genes and environment combine to influence human health and disease. Twin registries and international collaboration through existing networks can provide resources for achieving large sample sizes and access to expertise in study design and analysis of twin data.
Subject: Gêmeos
Sistema musculoesquelético - Doenças
Cooperação internacional
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: EEF - DEPARTAMENTO DE FISIOTERAPIA
Rights: Acesso Restrito
metadata.dc.identifier.doi: https://doi.org/10.1016/j.bjpt.2017.12.004
URI: http://hdl.handle.net/1843/48808
Issue Date: May-2018
metadata.dc.url.externa: https://www.sciencedirect.com/science/article/pii/S1413355517306299?via%3Dihub
metadata.dc.relation.ispartof: Brazilian Journal of Physical Therapy
Appears in Collections:Artigo de Periódico

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