Use of exhaled air as an improved biomonitoring method to assess perchloroethylene short-term exposure

Claúdia Maria Dias Paes; Helvécio Costa Menezes; Zenilda de Lourdes Cardeal

Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/48956

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DC Field	Value	Language
dc.creator	Claúdia Maria Dias Paes	pt_BR
dc.creator	Helvécio Costa Menezes	pt_BR
dc.creator	Zenilda de Lourdes Cardeal	pt_BR
dc.date.accessioned	2023-01-17T12:36:27Z	-
dc.date.available	2023-01-17T12:36:27Z	-
dc.date.issued	2017	-
dc.citation.volume	156	pt_BR
dc.citation.spage	108	pt_BR
dc.citation.epage	112	pt_BR
dc.identifier.doi	https://doi.org/10.1016/j.envres.2017.03.025	pt_BR
dc.identifier.issn	0013-9351	pt_BR
dc.identifier.uri	http://hdl.handle.net/1843/48956	-
dc.description.resumo	This paper shows the use of exhaled air as a biomonitoring method to assess perchloroethylene (PERC) environmental and occupational exposure. A sensitive, fast, and solvent free analytical method was developed to determine PERC in ambient and exhaled air of individuals occupationally exposed. The developed method used cold fiber solid phase microextraction (CF-SPME) as the sampling technique, and a standard permeation method to simulation of air matrix. The analysis were conducted by gas chromatography coupled to mass spectrometry (GC/MS). The methods were validated and were found to be precise, linear and sensitive for environmental and biological monitoring. The developed methods were applied to twenty-seven sampling points spread across Belo Horizonte city, Brazil, twenty four dry cleaners, an electroplating industry, a research laboratory, and an automotive paint preparation shop. The results of ambient air analyses ranging from 14.0 to 3205.0 µg m−³ with median concentration of 599.0 µg m−³. Furthermore, sampling of exhaled air of individuals occupationally exposed presented results ranging from 6.0 to 2635.0 µg m−³ with median concentration of 325.0 µg m−³. The strong correlation observed between ambient and exhaled air (r =0.930) demonstrates that exhaled air is a suitable biomarker for evaluating occupational exposure to PERC.	pt_BR
dc.description.sponsorship	CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico	pt_BR
dc.description.sponsorship	FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais	pt_BR
dc.description.sponsorship	CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior	pt_BR
dc.description.sponsorship	Outra Agência	pt_BR
dc.language	eng	pt_BR
dc.publisher	Universidade Federal de Minas Gerais	pt_BR
dc.publisher.country	Brasil	pt_BR
dc.publisher.department	ICX - DEPARTAMENTO DE QUÍMICA	pt_BR
dc.publisher.initials	UFMG	pt_BR
dc.relation.ispartof	Environmental Research	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.subject	Perchloroethylene	pt_BR
dc.subject	Ambient air	pt_BR
dc.subject	Exhaled air	pt_BR
dc.subject	Occupational exposure	pt_BR
dc.subject.other	Química analítica	pt_BR
dc.subject.other	Química ambiental	pt_BR
dc.subject.other	Monitoramento biológico	pt_BR
dc.subject.other	Monitoramento ambiental	pt_BR
dc.subject.other	Marcadores biológicos	pt_BR
dc.subject.other	Cromatografia de gás	pt_BR
dc.subject.other	Espectrometria de massa	pt_BR
dc.subject.other	Extração (Química)	pt_BR
dc.subject.other	Ar Análise	pt_BR
dc.subject.other	Saúde e trabalho	pt_BR
dc.title	Use of exhaled air as an improved biomonitoring method to assess perchloroethylene short-term exposure	pt_BR
dc.type	Artigo de Periódico	pt_BR
dc.url.externa	https://www.sciencedirect.com/science/article/pii/S0013935117305170	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0002-5759-612X	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0003-1383-6299	pt_BR
Appears in Collections:	Artigo de Periódico

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