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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/49356
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dc.creatorLianna Ghisi Gomespt_BR
dc.creatorNathalie Moro Bassil Dowerpt_BR
dc.creatorDeise Cristine Schroderpt_BR
dc.creatorDaiane Polettopt_BR
dc.creatorFelipe Gomes da Silvapt_BR
dc.creatorLuciana Dambrósio Guimarãespt_BR
dc.creatorRoberto Lopes de Souzapt_BR
dc.date.accessioned2023-02-01T13:40:54Z-
dc.date.available2023-02-01T13:40:54Z-
dc.date.issued2017-07-01-
dc.citation.volume11pt_BR
dc.citation.issue2pt_BR
dc.citation.spage129pt_BR
dc.citation.epage132pt_BR
dc.identifier.doihttps://doi.org/10.21708/avb.2017.11.2.6902pt_BR
dc.identifier.issn1981-5484pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/49356-
dc.description.resumoThis study evaluated the hematological and biochemical changes, the safety, as well as the change in propofol dose required for anesthesia induction in dogs, pretreated or not, in response to a single dose or continuous use of the nonsteroidal anti-inflammatory drug (NSAID) firocoxib. Thirty animals mean weighing 8.1 kg and mean aged 3.38 years were included. The animals were then divided into groups: Group I (GI) did not receive firocoxib, Group II (GII) received a single dose (5 mg/kg) 90 minutes before anesthesia induction, and Group III (GIII) received the same dose (5 mg/kg) for 40 consecutive days before induction of anesthesia with propofol. Hematological and biochemical evaluations were conducted. The times of collection were defined by the mean time of maximum concentration and constant concentration in the blood of the NSAID. All variables remained within the reference range, but averages differed statistically between GII and GIII, according to the Tukey test (p < 0.05). The average doses of propofol were 6.6 mg/kg, 6.1 mg/kg, and 7.8 mg/kg for GI, GII, and GIII, respectively. Hematological and biochemical changes and increased propofol dose for induction of anesthesia in GIII, despite this can be safely used in association with propofol at the time of anesthesic induction; which must be taken into account because it may also change doses of the drug in other anesthetic methods.pt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofActa Veterinaria Brasilicapt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherAnestesia veterináriapt_BR
dc.subject.otherAnestésicospt_BR
dc.subject.otherAgentes antiinflamatórios não esteróidespt_BR
dc.subject.otherCãespt_BR
dc.subject.otherHematologia veterináriapt_BR
dc.subject.otherBioquímica clínica veterináriapt_BR
dc.titleFirocoxib on hematological and biochemical parameters and anesthesia propofol dose in dogspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://periodicos.ufersa.edu.br/acta/article/view/6902pt_BR
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