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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/50509
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dc.creatorDaniela Valadão Freitas Rosapt_BR
dc.creatorLuiz Alexandre Viana Magnopt_BR
dc.creatorNathália Cristina Moreira Pereirapt_BR
dc.creatorLuiz Cláudio Ferreira Romanellipt_BR
dc.creatorMaicon Rodrigues Albuquerquept_BR
dc.creatorMarina Lobato Martins de Oliveirapt_BR
dc.creatorAnna Barbara de Freitas Carneiro Proiettipt_BR
dc.creatorRodrigo Nicolatopt_BR
dc.creatorAna Cristina Simões e Silvapt_BR
dc.creator‪Débora Marques de Mirandapt_BR
dc.date.accessioned2023-02-28T14:39:32Z-
dc.date.available2023-02-28T14:39:32Z-
dc.date.issued2018-
dc.citation.volume12pt_BR
dc.citation.issue5pt_BR
dc.citation.spage447pt_BR
dc.citation.epage454pt_BR
dc.identifier.doihttps://doi.org/10.2217/bmm-2017-0313pt_BR
dc.identifier.issn1752-0371pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/50509-
dc.description.resumoAim: The aim of this study is to evaluate the presence of a particular immunological profile in individuals long-term infected with HTLV-1, followed presenting different clinical courses. Materials & methods: Forty-eight individuals were evaluated for 19 cytokines analyzed in cerebrospinal fluid and plasma of patients with HTLV-1 presenting with and without neurological symptoms. Results: Proinflammatory cytokines and the chemokine ligand 11 (ITAC/CXCL11) were increased in individuals with HTLV-1 coursing with neurological symptoms. Conclusion: Different cytokines’ expression profile in the presence of neurological symptoms may help to understand and characterize the progression for severe clinical presentations.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE ESPORTESpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PSIQUIATRIA E NEUROLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofBiomarkers in Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectAntigens and antibodiespt_BR
dc.subjectCerebrospinal fluidpt_BR
dc.subjectHAM / TSPpt_BR
dc.subjectHTLpt_BR
dc.subjectImmune markerspt_BR
dc.subjectITACpt_BR
dc.subjectMyopathypt_BR
dc.subjectNeurological symptomspt_BR
dc.subjectPlasmapt_BR
dc.subject.otherAntigenospt_BR
dc.subject.otherAnticorpospt_BR
dc.subject.otherLíquido cefalorraquidianopt_BR
dc.subject.otherParaparesia espástica tropicalpt_BR
dc.subject.otherInfecção por HTLV-1pt_BR
dc.subject.otherCitocinaspt_BR
dc.subject.otherMúsculos - Doençaspt_BR
dc.subject.otherPlasmapt_BR
dc.titlePlasma and cerebrospinal fluid levels of cytokines as disease markers of neurologic manifestation in long-term HTLV-1 infected individualspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.futuremedicine.com/doi/10.2217/bmm-2017-0313?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmedpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3693-1897pt_BR
dc.identifier.orcidhttp://orcid.org/0000-0001-6021-8480pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9222-3882pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7081-8401pt_BR
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