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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/50726
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dc.creatorMaria Helena Franco Moraispt_BR
dc.creatorStefanne Aparecida Gonçalvespt_BR
dc.creatorHelen Maria de Oliveira Ramos Lopespt_BR
dc.creatorFrederico Figueiredo Amânciopt_BR
dc.creatorThais Almeida Marques da Silvapt_BR
dc.creatorCarlos Maurício Figueiredo Antunespt_BR
dc.creatorFernanda do Carmo Magalhãespt_BR
dc.creatorMariângela Carneiropt_BR
dc.date.accessioned2023-03-08T00:31:23Z-
dc.date.available2023-03-08T00:31:23Z-
dc.date.issued2020-02-29-
dc.citation.volume114pt_BR
dc.citation.issue5pt_BR
dc.citation.spage346pt_BR
dc.citation.epage354pt_BR
dc.identifier.doihttps://doi.org/10.1093/trstmh/traa010pt_BR
dc.identifier.issn1878-3503pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/50726-
dc.description.resumoBackground: The aim of this study was to identify the prognostic factors associated with death from visceral leishmaniasis (VL) considering the clinical evolution of patients through a case-control study. Methods: We randomly selected 180 cases (death caused by VL) and 180 controls (cured) from Belo Horizonte's hospitals in Brazil, according to data found in the patients' medical records. Five models of multivariate logistic regression were performed following the chronological order of the variables between the onset of the symptoms and evolution of the VL cases. Results: Considering the multivariate models and the stages of clinical evolution of VL, the prognostic factors associated with death are: age >60 y, minor hemorrhagic phenomena, increased abdominal volume, jaundice, dyspnea, malnutrition, TB, billirubin >2 mg/dL, Aspartate Aminotransferase (AST) or Alanine Aminotransferase (ALT) >100 U/L, leukocytes >7000/mm3, hemoglobin <7 g/dL, platelets <50 000/mm3 and infection without defined focus and bleeding. Conclusions: Knowledge regarding the prognostic factors associated with death from VL in different stages of the disease in large Brazilian urban centers such as Belo Horizonte may help optimize patient management strategies and contribute to reduce the high fatality rates in these cities.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE PARASITOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofTransactions of the Royal Society of Tropical Medicine and Hygiene-
dc.rightsAcesso Restritopt_BR
dc.subject.otherEstudos de Casos e Controlespt_BR
dc.subject.otherLeishmaniose Visceralpt_BR
dc.subject.otherPrognósticopt_BR
dc.titlePrognostic factors associated with death from visceral leishmaniasis: a case-control study in Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://academic.oup.com/trstmh/article/114/5/346/5766439pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5042-2004pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3286-8683pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5732-7173pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6025-2774pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9390-7714pt_BR
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