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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/51062
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dc.creatorCamila Alessandra Pazzinipt_BR
dc.creatorLuciano José Pereirapt_BR
dc.creatorTarcília Aparecida da Silvapt_BR
dc.creatorCarina Cristina Montalvany-Antonuccipt_BR
dc.creatorSoraia Macaript_BR
dc.creatorLeandro Silva Marquespt_BR
dc.creatorSaul Martins de Paivapt_BR
dc.date.accessioned2023-03-20T19:35:16Z-
dc.date.available2023-03-20T19:35:16Z-
dc.date.issued2017-07-
dc.citation.volume79pt_BR
dc.citation.spage30pt_BR
dc.citation.epage34pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.archoralbio.2017.02.017pt_BR
dc.identifier.issn00039969pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/51062-
dc.description.resumoAims: The aim of the present study was to investigate the effect of probiotic (Bacillus Subtilis) supplementation on bone remodelling induced by mechanical loading. Methods: C57BL/6 mice were divided in two groups: (1) Probiotic and (2) Vehicle (water). The probiotic (1.5×108CFU/mL) was administered orally for 14 days, starting two days before the induction of orthodontic tooth movement (OTM). OTM was determined by histomorphometric analysis by comparing the right to the left side of the maxilla. The number of osteoclasts was determined by counting TRAP-positive cells. Osteoblasts were counted on Masson's trichrome-stained slides. Results: OTM was similar between groups (with and without probiotic supplementation) (p=0.46). The number of TRAP-positive cells increased (p<0.01) on the experimental side (where the spring coil was installed) in comparison to the control side in both groups. However, the number of osteoclasts decreased (p˂0.01) in the probiotic group, in comparison to the vehicle group. There was an increase in the number of osteoblasts (p˂0.05) in both the Vehicle and Probiotic groups on the side under OTM, independent of probiotic supplementation.Conclusion: Oral Supplementation with a probiotic influenced the number of osteoclasts adjacent to the tooth root during orthodontic movement in mice.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofArchives of Oral Biologypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectConsumo de probióticospt_BR
dc.subjectOsteoclastospt_BR
dc.subjectMovimento ortodônticopt_BR
dc.subjectMicrobiologia oralpt_BR
dc.subjectFarmacologiapt_BR
dc.subjectPatologia Bucalpt_BR
dc.subject.otherTooth movement techniquespt_BR
dc.subject.otherProbioticspt_BR
dc.subject.otherOsteoclastspt_BR
dc.subject.otherOrthodonticspt_BR
dc.subject.otherOsteoblastspt_BR
dc.titleProbiotic consumption decreases the number of osteoclasts during orthodontic movement in micept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0003996917300559?via%3Dihubpt_BR
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