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http://hdl.handle.net/1843/51280| Type: | Artigo de Periódico |
| Title: | Diet supplementation with madagascar cockroach flour (Gromphadorhina portentosa) improved malnourished mice metabolism and ameliorated liver inflammatory markers |
| Authors: | Janaína Ribeiro Oliveira Júnio Cota Silva Bruna Mara Carvalho Theles de Oliveira Costa Diego Vicente da Costa Sérgio Henrique Sousa Santos |
| Abstract: | Background: Malnutrition and accessible high-quality protein food sources are two of the world's alimentary challenges. Edible insects are nowadays recognized as a possible functional food solution with lower environmental impacts and beneficial health effects. Objective: In this context, the aim of the present study is to evaluate Madagascar cockroach (Gromphadorhina portentosa) flour supplementation effects on a malnourished mice model, considering its effects on metabolism, adiposity, and inflammatory liver profiles. Method: Male Swiss mice are divided into five groups and fed with experimental diets for eight weeks, including a standard diet (ST) ad libitum, AIN93 ad libitum (AIN), insect flour-enriched AIN93 (AIN+IM), AIN-40% feed restriction (AIN-FR), and insect flour-enriched AIN-40% of feed restriction (AIN-FR+IM). The metabolic profiles, adipose tissue, biochemical parameters, and liver IL-6 and IL-10 expression are evaluated. Results: The main findings show a body weight and metabolism improvement followed by an increased recovery of the adipocyte area in the AIN-FR+IM group when compared to the AIN-FR malnourished group. Reduced hepatic IL-6 and increased IL-10 expression are also detected in the AIN-FR+IM group. Conclusion: The results show that insect flour supplementation enhances both body weight and adiposity gain/recovery. The results also show hepatic improvement of inflammatory markers. |
| Subject: | Insetos comestíveis Barata Desnutrição Dieta de alto teor proteico Fígado -- Doenças |
| language: | por |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | http://doi.10.2174/2772574X12666211210160819 |
| URI: | http://hdl.handle.net/1843/51280 |
| Issue Date: | 2021 |
| metadata.dc.url.externa: | https://www.eurekaselect.com/article/119355 |
| metadata.dc.relation.ispartof: | Recent Patents on Food, Nutrition & Agriculture |
| Appears in Collections: | Artigo de Periódico |
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