Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/51442
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dc.creatorValdir de Aquino Lemospt_BR
dc.creatorRonaldo Vagner Thomatieli dos Santospt_BR
dc.creatorHanna Karen Moreira Antunespt_BR
dc.creatorClaus Behnpt_BR
dc.creatorGinés Viscorpt_BR
dc.creatorFabio Santos Lirapt_BR
dc.creatorIrene Guarido Luz Bittarpt_BR
dc.creatorAline Venticinque Carispt_BR
dc.creatorSergio Tufikpt_BR
dc.creatorMarco Tulio De Mellopt_BR
dc.date.accessioned2023-03-31T16:34:59Z-
dc.date.available2023-03-31T16:34:59Z-
dc.date.issued2018-11-
dc.citation.volume196pt_BR
dc.citation.spage95pt_BR
dc.citation.epage103pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.physbeh.2018.08.016pt_BR
dc.identifier.issn0031-9384pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/51442-
dc.description.resumoThis work evaluated the effects of moderate physical exercise performed under hypoxic conditions on melatonin and sleep. Forty healthy men were randomized into four groups: Normoxia (N) (n = 10); Hypoxia (H) (n = 10); Exercise under Normoxia (EN) (n = 10); and Exercise under Hypoxia (EH) (n = 10). The observation period for all groups was approximately 36 h, beginning with a first night devoid of any intervention. Aerobic exercise was performed by the EN and EH groups on a treadmill at 50% of the ventilatory threshold intensity for 60 min. Sleep evaluation was performed on the 1st and 2nd nights. Venous blood samples for the melatonin measurement were obtained on the 1st and 2nd days at 7:30 AM as well as on the 1st and 2nd nights at 10:30 PM. On the 2nd night, melatonin was higher in the H group than in the N group, but both were lower than values of the EH group. The nocturnal iThis work evaluated the effects of moderate physical exercise performed under hypoxic conditions on melatonin and sleep. Forty healthy men were randomized into four groups: Normoxia (N) (n = 10); Hypoxia (H) (n = 10); Exercise under Normoxia (EN) (n = 10); and Exercise under Hypoxia (EH) (n = 10). The observation period for all groups was approximately 36 h, beginning with a first night devoid of any intervention. Aerobic exercise was performed by the EN and EH groups on a treadmill at 50% of the ventilatory threshold intensity for 60 min. Sleep evaluation was performed on the 1st and 2nd nights. Venous blood samples for the melatonin measurement were obtained on the 1st and 2nd days at 7:30 AM as well as on the 1st and 2nd nights at 10:30 PM. On the 2nd night, melatonin was higher in the H group than in the N group, but both were lower than values of the EH group. The nocturnal increase in melatonin was inversely correlated with the oxygen saturation of hemoglobin (SaO2%) on the 2nd night in the H group and on the 2nd day in the EH group. Diurnal remission of nocturnal melatonin appeared to be postponed in the H group and even more so in the EH group. Thus, normobaric hypoxia, which is equivalent to oxygen availability at an altitude of 4500 m, acutely increases melatonin. Moreover, diurnal remission of the nocturnal increase in melatonin seems to be delayed by hypoxia alone but even more so when acting together with exercise.pt_BR
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulopt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE ESPORTESpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPhysiology & Behaviorpt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectHypoxiapt_BR
dc.subjectExercisept_BR
dc.subjectMelatoninpt_BR
dc.subject.otherHipóxiapt_BR
dc.subject.otherExercícios físicospt_BR
dc.subject.otherMelatoninapt_BR
dc.titleMelatonin and sleep responses to normobaric hypoxia and aerobic physical exercise: a randomized controlled trialpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0031938418306942pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9974-0049pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7010-2799pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6648-0957pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4942-2346pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9645-1003pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9314-3195pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4012-495pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3896-2208pt_BR
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