Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/52842
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dc.creatorBerenilde Valéria de Oliveira Sousapt_BR
dc.creatorDaniela Fernanda de Freitaspt_BR
dc.creatorRenato Sobral Monteiro Júniorpt_BR
dc.creatorIara Heloisa Ramos Mendespt_BR
dc.creatorJaciara Neves Sousapt_BR
dc.creatorVictor Hugo Dantas Guimarãespt_BR
dc.creatorSérgio Henrique Sousa Santospt_BR
dc.date.accessioned2023-05-05T12:16:53Z-
dc.date.available2023-05-05T12:16:53Z-
dc.date.issued2021-05-20-
dc.citation.volume48pt_BR
dc.citation.spage4625pt_BR
dc.citation.epage4635pt_BR
dc.identifier.doihttps://doi.org/10.1007/s11033-021-06400-2pt_BR
dc.identifier.issn1573-4978pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/52842-
dc.description.resumoNeutrophil extracellular traps (NETs) represent an innate organism defense mechanism characterized by neutrophil release of intracellular material to capture any aggressor agent. Elevated NETs release is associated with increased inflammatory response and related diseases, such as obesity. Chronic physical training is one of the main strategies to treat and prevent obesity. The relationship between physical training and NETs is still under study. The present review, followed by a bioinformatics analysis, demonstrates the meaningful connection between physical exercise, obesity, and NETs. The bioinformatics indicated TNF-α as a leading gene after the ontological analysis followed by positive-interleukin-6 regulation, chemokines, and inflammatory response regulation. The main results pointed to a relevant regulatory effect of physical training on NETs release, indicating physical exercise as a possible therapeutic target on modulating NETs and inflammation.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofMolecular Biology Reports-
dc.rightsAcesso Restritopt_BR
dc.subject.otherExercícios físicospt_BR
dc.subject.otherObesidadept_BR
dc.subject.otherInflamaçãopt_BR
dc.subject.otherNeutrófilospt_BR
dc.subject.otherBioinformáticapt_BR
dc.titlePhysical exercise, obesity, inflammation and neutrophil extracellular traps (NETs): a review with bioinformatics analysispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s11033-021-06400-2pt_BR
Appears in Collections:Artigo de Periódico

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