Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/53504
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dc.creatorThaís Resendebatistapt_BR
dc.creatorSandhi Maria Barretopt_BR
dc.creatorAna Paula Ferreira Silvapt_BR
dc.creatorWander Valadares de Oliveira Juniorpt_BR
dc.creatorChams Bicalho Malufpt_BR
dc.creatorAntonio Luiz Pinho Ribeiropt_BR
dc.creatorMaria Das Graças Carvalhopt_BR
dc.creatorRoberta Carvalho de Figueiredopt_BR
dc.creatorDanyelle Romana Alves Riospt_BR
dc.date.accessioned2023-05-17T19:25:03Z-
dc.date.available2023-05-17T19:25:03Z-
dc.date.issued2021-03-08-
dc.citation.volume10pt_BR
dc.citation.issue9pt_BR
dc.citation.spage1pt_BR
dc.citation.epage22pt_BR
dc.identifier.doi10.33448/rsd-v10i9.17888pt_BR
dc.identifier.issn25253409pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/53504-
dc.description.abstractIntrodução: O teste de geração de trombina (TGT) avalia o risco de desenvolvimento de eventos trombóticos. O objetivo deste estudo foi investigar a associação entre o uso de contraceptivos orais (COs) e a terapia hormonal (TH)com a TGT e a resistência à proteína C ativada (PCa). Métodos: Estudo transversal com mulheres do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). A TGT foi realizada pelo método CAT. Resultados: Houve associação entre todos os parâmetros do TGT e o uso de COs e associação do tempo de latência e pico com o uso de TH. Conclusão: A TGT permite avaliar o estado de hipercoagulabilidade e pode ser útil no manejo de usuárias de hormônios femininospt_BR
dc.description.resumoIntroduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CAT method. Results: There was an association between all parameters of the TGA and the use of OCs and an association of lag time and peak time with the use of HT. Conclusion: The TGA allows us to assess the hypercoagulability status and may be useful in the management of female hormones users.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTARpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofResearch, Society and Development-
dc.rightsAcesso Abertopt_BR
dc.subjectContraceptives,pt_BR
dc.subjectOralpt_BR
dc.subjectHormone replacement therapypt_BR
dc.subjectBlood coagulation testspt_BR
dc.subject.otherAnticoncepcionais Oraispt_BR
dc.subject.otherTerapia de Reposição Hormonalpt_BR
dc.subject.otherTestes de Coagulação Sanguíneapt_BR
dc.titleAssociation between the use of female hormones and the thrombin generation: cross-sectional analysis of the longitudinal study on adult health (ELSA-Brasil)pt_BR
dc.title.alternativeAssociação entre o uso de contraceptivos orais e terapia hormonal e a geração de trombina: Análise transversal do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil)pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://rsdjournal.org/index.php/rsd/article/view/17888pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3690-2554pt_BR
Appears in Collections:Artigo de Periódico

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