Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/55695
Type: | Artigo de Periódico |
Title: | Efficacy of B-lactam/B-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum B-lactamase-producing enterobacteriaceae in hematological patients with neutropenia |
Authors: | Carlotagudiol Pilar Martín-dávila Alison Freifeld Lucía Gómez Thomas Gottlieb Mercè Gurguí Fabián Herrera Adriana Manzur Georg Maschmeyer Yolanda Meije Miguel Montejo Cristina Royo-cebrecos Maddalena Peghin Jesús Rodríguez-baño Isabel Ruiz-camps Teresa c. Sukiennik Cristian Tebe Jordi Carratalà Edson Abdala Murat Akova Rocío Álvarez Guillermo Maestro-de la Calle Angela Cano Carlos Cervera Wanessa Trindade Clemente |
Abstract: | ß-Lactam/ß-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum- -lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem sparing alternatives for the treatment of BSI due to ESBLs in these patients. |
Subject: | Sepse Neutropenia Inibidores de beta-Lactamases |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | MED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR |
Rights: | Acesso Aberto |
metadata.dc.identifier.doi: | 10.1128/aac.00164-17 |
URI: | http://hdl.handle.net/1843/55695 |
Issue Date: | 7-May-2017 |
metadata.dc.url.externa: | https://journals.asm.org/doi/10.1128/aac.00164-17 |
metadata.dc.relation.ispartof: | Antimicrobial Agents and Chemotherapy |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Efficacy of B-Lactam B-Lactamase pdfa.pdf | 724.6 kB | Adobe PDF | View/Open |
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