Efficacy of B-lactam/B-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum B-lactamase-producing enterobacteriaceae in hematological patients with neutropenia

Carlotagudiol; Pilar Martín-dávila; Alison Freifeld; Lucía Gómez; Thomas Gottlieb; Mercè Gurguí; Fabián Herrera; Adriana Manzur; Georg Maschmeyer; Yolanda Meije; Miguel Montejo; Cristina Royo-cebrecos; Maddalena Peghin; Jesús Rodríguez-baño; Isabel Ruiz-camps; Teresa c. Sukiennik; Cristian Tebe; Jordi Carratalà; Edson Abdala; Murat Akova; Rocío Álvarez; Guillermo Maestro-de la Calle; Angela Cano; Carlos Cervera; Wanessa Trindade Clemente

Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/55695

Tipo:	Artigo de Periódico
Título:	Efficacy of B-lactam/B-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum B-lactamase-producing enterobacteriaceae in hematological patients with neutropenia
Autor(es):	Carlotagudiol Pilar Martín-dávila Alison Freifeld Lucía Gómez Thomas Gottlieb Mercè Gurguí Fabián Herrera Adriana Manzur Georg Maschmeyer Yolanda Meije Miguel Montejo Cristina Royo-cebrecos Maddalena Peghin Jesús Rodríguez-baño Isabel Ruiz-camps Teresa c. Sukiennik Cristian Tebe Jordi Carratalà Edson Abdala Murat Akova Rocío Álvarez Guillermo Maestro-de la Calle Angela Cano Carlos Cervera Wanessa Trindade Clemente
Resumo:	ß-Lactam/ß-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum- -lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem sparing alternatives for the treatment of BSI due to ESBLs in these patients.
Assunto:	Sepse Neutropenia Inibidores de beta-Lactamases
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Instituição:	UFMG
Departamento:	MED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR
Tipo de Acesso:	Acesso Aberto
Identificador DOI:	10.1128/aac.00164-17
URI:	http://hdl.handle.net/1843/55695
Data do documento:	7-Mai-2017
metadata.dc.url.externa:	https://journals.asm.org/doi/10.1128/aac.00164-17
metadata.dc.relation.ispartof:	Antimicrobial Agents and Chemotherapy
Aparece nas coleções:	Artigo de Periódico

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