1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/56150
Full metadata record
DC FieldValueLanguage
dc.creatorSimone Becho de Campospt_BR
dc.creatorPaulo Marcos Brasil Rochapt_BR
dc.creatorFernando Silva Nevespt_BR
dc.creatorDebora Marques Mirandapt_BR
dc.creatorHumberto Corrêa da Silva Filhopt_BR
dc.date.accessioned2023-07-12T21:41:21Z-
dc.date.available2023-07-12T21:41:21Z-
dc.date.issued2017-
dc.citation.volume14pt_BR
dc.citation.issue6pt_BR
dc.citation.spage909pt_BR
dc.citation.epage910pt_BR
dc.identifier.doihttps://doi.org/10.4306/pi.2017.14.6.909pt_BR
dc.identifier.issn17383684pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/56150-
dc.description.resumoThe ACP1 gene is expressed in fetal and adult brain, and belongs to a phosphotyrosine protein phosphatase family that acts regulating β-catenin levels. Increased amounts of ACP1 result in decreased β-catenin in the cytoplasm,1 which is the opposite effect of the administration of lithium. For these reasons the ACP1 seems a candidate gene to be associ ated both to bipolar disorder as well suicide behavior.A recent Genome-Wide association study of attempt sui cide in bipolar patients found a significantly association with the 2p25 region which SNPs fall in a large linkage disequilib rium with a block containing the acid phosphatase 1 (ACP1) gene region. Furthermore a microarray study show ACP1 levels significantly increased in the brains of patients who committed suicide.2The aim of our study was to evaluate whether ACP1 gene polymorphisms are associated to BD and/or suicide attempt in bipolar disorder patients in a different population sample.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PSIQUIATRIA E NEUROLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPsychiatry Investigation-
dc.rightsAcesso Abertopt_BR
dc.subjectGene Polymorphismpt_BR
dc.subjectSuicidept_BR
dc.subjectBipolar Disorderpt_BR
dc.subject.otherPolimorfismo Genéticopt_BR
dc.subject.otherSuicídiopt_BR
dc.subject.otherTranstorno Bipolarpt_BR
dc.titleACP1 gene polymorphism associated with suicide attempt type in bipolar disorder patients.pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.psychiatryinvestigation.org/journal/view.php?doi=10.4306/pi.2017.14.6.909pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2757-1375pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
ACP1 Gene Polymorphism Associated with Suicide pdfa.pdf110.75 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.