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http://hdl.handle.net/1843/56199| Type: | Artigo de Periódico |
| Title: | Cognitive performance of community-dwelling oldest-old individuals with major depression: the pietà study |
| Authors: | Filipi Leles da Costa Dias Antônio Lúcio Teixeira Henrique Cerqueira Guimarães Maira Tonidandel Barbosa Elisa de Paula França Resende Rogério Gomes Beato Karoline Carvalho Carmona Paulo Caramelli |
| Abstract: | Background: Individuals with late-life depression (LLD) may present cognitive symptoms. We sought to determine whether a brief cognitive battery (BCB) could identify cognitive and functional deficits in oldest old individuals with LLD and a low level of education. Methods: We evaluated 639 community-dwelling individuals aged 75+ years in Caeté (MG), Brazil. We used the MINI and GDS-15 to diagnose major depression and evaluate its severity, respectively. The cognitive evaluation comprised the Mini-Mental State Examination (MMSE), BCB, clock-drawing test, category fluency test (animals) and Pfeffer’s Functional Activities Questionnaire (FAQ). Results: Fifty-four (11.6%) of the included individuals were diagnosed with LLD; on average, these participants were aged 81.0 ± 4.8 years and had 3.9 ± 3.4 years of schooling, and 77.8% of the subjects with LLD were female. Depressed individuals scored lower than subjects without dementia/depression on the MMSE overall (p < 0.001) and on several of the MMSE subscales, namely, time (p < 0.001) and spatial orientation (p = 0.021), attention/calculation (p = 0.019), and language (p = 0.004). Individuals with LLD performed worse on the incidental and (p = 0.011) immediate memory (p = 0.046) and learning tasks (p = 0.039) of the BCB. Individuals with LLD also performed worse on the category fluency test (p =0.006), clock-drawing test (p = 0.011) and FAQ (p < 0.001). Depression severity was negatively correlated with incidental memory (ρ = −0.412; p = 0.003) and positively correlated with FAQ score (ρ = 0.308; p = 0.035). In the multiple regression analysis, only temporal orientation and FAQ score remained independently associated with LLD. Conclusion: Individuals with depression and a low level of education presented several cognitive and functional deficits. Depression severity was negatively correlated with incidental memory and functionality. Our findings serve as a description of the presence of cognitive dysfunction in individuals with LLD and suggest that these deficits may be identified based on the results of a BCB. |
| Subject: | Depressao Transtornos Cognitivos Idoso de 80 Anos ou mais |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE CLÍNICA MÉDICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1017/S1041610217000850 |
| URI: | http://hdl.handle.net/1843/56199 |
| Issue Date: | 1-Jun-2017 |
| metadata.dc.url.externa: | https://www.cambridge.org/core/journals/international-psychogeriatrics/article/abs/cognitive-performance-of-communitydwelling-oldestold-individuals-with-major-depression-the-pieta-study/1D47593BBDDE78FA4549C86121F81B43#access-block |
| metadata.dc.relation.ispartof: | International Psychogeriatrics |
| Appears in Collections: | Artigo de Periódico |
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