Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/56382| Type: | Artigo de Periódico |
| Title: | Investigation of cobalt(iii)-triazole systems as prototypes for hypoxia-activated drug delivery |
| Authors: | Isabela Cristina Aguiar de Souza Borguignon Letícia Villafranca Faro Daniel Tadeu Gomes Gonzaga Carlos Basílio Pinheiro Fernando de Carvalho da Silva Vitor Francisco Ferreira Fabio da Silva Miranda Marciela Scarpellini Mauricio Lanznaster |
| Abstract: | Three novel cobalt(III)-triazole complexes with structural and redox properties suitable for hypoxia-activated drug delivery were obtained. A major influence of the ancillary ligands (TPA, py2en, py2 enMe2 ) on the electronic properties and reactivity of their complexes was observed. An [O2 ]-dependent reduction to cobalt(II) by ascorbic acid provided evidence of hypoxic selectivity. |
| Subject: | Cobalto Câncer Anoxemia |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICX - DEPARTAMENTO DE FÍSICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1039/c6dt02456d |
| URI: | http://hdl.handle.net/1843/56382 |
| Issue Date: | 2016 |
| metadata.dc.url.externa: | https://pubs.rsc.org/en/content/articlelanding/2016/DT/C6DT02456D |
| metadata.dc.relation.ispartof: | Dalton Transactions |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.