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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/56641
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dc.creatorFelipe A. Moraespt_BR
dc.creatorMichael R. R. da Silvapt_BR
dc.creatorJéssica B. R. dos Santospt_BR
dc.creatorFrancisco de Assis Acurciopt_BR
dc.creatorAlessandra Maciel Almeidapt_BR
dc.creatorAdriana Maria Kakehasipt_BR
dc.creatorJuliana Alvares Teodoropt_BR
dc.date.accessioned2023-07-18T20:31:08Z-
dc.date.available2023-07-18T20:31:08Z-
dc.date.issued2021-
dc.citation.volume26pt_BR
dc.citation.spage135pt_BR
dc.citation.epage141pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.vhri.2021.06.003pt_BR
dc.identifier.issn2212-1102pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/56641-
dc.description.resumoObjectives: To assess the quality of life (QOL) and its associated factors in patients with psoriatic arthritis (PsA) who would start treatment with biologic drugs at the Brazilian Unified Health System. Methods: A cross-sectional study was performed at a single center pharmacy in Belo Horizonte, State of Minas Gerais, Brazil. EQ-5D was used to assess the patients’ QOL. The functional status was assessed using the Health Assessment Questionnaire Disability Index, whereas disease activity was evaluated through the Bath Ankylosing Spondylitis Disease Activity Index and the Clinical Disease Activity Index. Simple and multiple linear regression analyses were performed to assess the factors associated with QOL. Results: A total of 212 patients with PsA were included, of which 185 (87.3%) reported having some pain/discomfort, and 148 (69.8%) presented some level of anxiety/depression. Patients with PsA had a mean QOL score of 0.651 (SD 0.12) with a sig nificant reduction in female patients, concomitant use of nonsteroidal anti-inflammatory drugs, comorbidity, and worse clinical and functional status. Poor QOL was associated with worse functional status by the Health Assessment Questionnaire-Disability Index, disease activity by the Bath Ankylosing Spondylitis Disease Activity Index, and with diagnoses of osteoporosis, hypothyroidism, and depression. Conclusion: PsA and its associated comorbidities negatively affect the QOL, evidencing the need for a comprehensive and effective clinical approach.pt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTORpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofValue in Health Regional Issuespt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCross-sectional studypt_BR
dc.subjectHealth systempt_BR
dc.subjectPsoriatic arthritispt_BR
dc.subjectQuality of lifept_BR
dc.subject.otherArtritept_BR
dc.subject.otherQualidade de vidapt_BR
dc.titleHealth-related quality of life in psoriatic arthritis: findings and implicationspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212109921000935#:~:text=When%20compared%20with%20the%20general,and%20significantly%20increased%20mortality%20rate.pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5880-5261pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0138-9401pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9411-7493pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0210-0721pt_BR
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