Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57050
Type: Artigo de Periódico
Title: AISI 304 stainless steel as a transducer substrate in electrochemical biosensors for medical applications
Authors: Ricardo Adriano Dorledo de Faria
Luiz Guilherme Dias Heneine
Vanessa de Freitas Cunha Lins
Tulio Matencio
Abstract: Stainless Steels (SS) are promising candidates to constitute the transducer substrate of devices for electrochemical sensing mainly due to their high electrical conductivity, biocompatibility and relative low cost. In this study, the corrosion resistance of SS was examined in four solutions that represent the environment of biosensors in real applications: 0.01 M Tris buffer (pH 7.4), an electrolyte containing Tris and 0.1M KCl as supporting source of ions, Hanks’ solution to simulate body fluids and, also, a solution to represent the electrolyte commonly used to performed Cyclic Voltammetry (CV). Potentiodinamic anodic polarization, Chronoamperometry and images of Optical Microscopy revealed that the Hanks’ and CV solutions were the most aggressive media to the SS electrodes, which remained chemically stable in both Tris and electrolyte during 16h under the influence of critical potentials. When functionalized to recognize venom from Crotalus snakes, the SS suffered an increase of the diameter of the capacitive arc in the EIS experiment as a result of the detection of the target analyte, corroborating it is a promising electrochemical transducer for application in biosensors.
Subject: Ciência dos materiais
Biossensores
Aço inoxidável
Detectores eletroquímicos
Análise eletroquímica
Voltametria
Tecnologia médica
Aço - Corrosão
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: ENG - DEPARTAMENTO DE ENGENHARIA QUÍMICA
ICX - DEPARTAMENTO DE QUÍMICA
Rights: Acesso Aberto
metadata.dc.identifier.doi: http://dx.doi.org/10.26717/BJSTR.2019.18.003117
URI: http://hdl.handle.net/1843/57050
Issue Date: May-2019
metadata.dc.url.externa: https://biomedres.us/fulltexts/BJSTR.MS.ID.003117.php
metadata.dc.relation.ispartof: Biomedical Journal of Scientific & Technical Research
Appears in Collections:Artigo de Periódico



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