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http://hdl.handle.net/1843/57191
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DC Field | Value | Language |
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dc.creator | José Ricardoborém Lopes | pt_BR |
dc.creator | Lucas Garcia de Figueiredo Colin | pt_BR |
dc.creator | Alexandre Rodrigues Ferreira | pt_BR |
dc.creator | Priscila Menezes Ferri Liu | pt_BR |
dc.creator | Thaís Costa Nascentes Queiroz | pt_BR |
dc.creator | Eleonora Druve Tavares Fagundes | pt_BR |
dc.creator | Júlio Rocha Pimenta | pt_BR |
dc.creator | José Andrade Franco Neto | pt_BR |
dc.creator | Simone Diniz Carvalho | pt_BR |
dc.creator | Maria Eduarda Marques Borges | pt_BR |
dc.date.accessioned | 2023-07-28T23:43:18Z | - |
dc.date.available | 2023-07-28T23:43:18Z | - |
dc.date.issued | 2020 | - |
dc.citation.issue | 72 | pt_BR |
dc.citation.spage | 802 | pt_BR |
dc.citation.epage | 806 | pt_BR |
dc.identifier.doi | 10.1097/mpg.0000000000003039 | pt_BR |
dc.identifier.issn | 02772116 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/57191 | - |
dc.description.resumo | Objectives: To evaluate non-invasive predictive factors of varices with a high risk of bleeding in pediatric cirrhotic patients.Methods: This retrospective, cross-sectional study included data from 158 children with cirrhosis, median age of 5.38 years (interquartile [IQ]2.0811.52 years), and no history of upper gastrointestinal bleeding.Patients underwent an endoscopy to screen for esophageal varices. Varices with a high risk of bleeding were defined as those with a medium to large caliber, presence of red spots, or the presence of gastric varices and identified as high-risk varices (HRV). Laboratory and clinical factors were evaluated as possible predictors of HRV. Results: HRV were detected in 30 children (19%) after the first endoscopy. In the multivariate analysis, only the risk score (RS), as described by Park et al, and the aspartate aminotransferase-to-platelet ratio index (APRi) were predictive of HRV. The best non-invasive predictor of HRV was the RS with an area under the receiver operating characteristic curve of 0.764. When used a cut-off point of 1.2, the sensitivity of the RS was 90% and specificity was 53%. The use of RS or APRi correctly identified 96% of children with HRV. Conclusions: The described predictors allow the correct identification of patients with HRV. The association of RS >1.2 or APRi >1.4 has a good sensitivity to identify HRV and to prevent unnecessary endoscopy in about one-third of children with no HRV. | pt_BR |
dc.format.mimetype | pt_BR | |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | MED - DEPARTAMENTO DE PEDIATRIA | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | Journal of Pediatric Gastroenterology and Nutrition | - |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | Children | pt_BR |
dc.subject | Esophageal varices | pt_BR |
dc.subject | Liver cirrhosis | pt_BR |
dc.subject.other | Crianças | pt_BR |
dc.subject.other | Varizes Esofágicas e Gástricas | pt_BR |
dc.subject.other | Cirrose Hepática | pt_BR |
dc.title | Non-invasive predictors of esophageal varices with a high risk of bleeding in pediatric cirrhotic patients | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | https://journals.lww.com/jpgn/Fulltext/2021/06000/Non_invasive_Predictors_of_Esophageal_Varices_With.5.aspx | pt_BR |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Non invasive predictors of esophageal varices with a high risk of bleeding in pediatric cirrhotec patients pdfa.pdf | 97.08 kB | Adobe PDF | View/Open |
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