1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57197
Full metadata record
DC FieldValueLanguage
dc.creatorLudmila Maria Diniz Leroypt_BR
dc.creatorJoão Alexandre Ribeiro Gonçalves Barbosapt_BR
dc.creatorGonzalo de Prat Gaypt_BR
dc.creatorIgor Polikarpovpt_BR
dc.creatorCarlos Basílio Pinheiropt_BR
dc.date.accessioned2023-07-31T12:02:52Z-
dc.date.available2023-07-31T12:02:52Z-
dc.date.issued2019-
dc.citation.volume88pt_BR
dc.citation.issue1pt_BR
dc.citation.spage106pt_BR
dc.citation.epage112pt_BR
dc.identifier.doihttps://doi.org/10.1002/prot.25773pt_BR
dc.identifier.issn1097-0134pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57197-
dc.description.resumoBovine papillomavirus proteins were extensively studied as a prototype for the human papillomavirus. Here, the crystal structure of the extended E2 DNA-binding domain of the dominant transcription regulator from the bovine papillomavirus strain 1 is described in the space group P3121. We found two protein functional dimers packed in the asymmetric unit. This new protein arrangement inside the crystal led to the reduction of the mobility of a previously unobserved loop directly involved in the protein-DNA interaction, which was then modeled for the first time.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE FÍSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPROTEINS: Structure, Function, and Bioinformatics-
dc.rightsAcesso Restritopt_BR
dc.subjectBovine papillomaviruspt_BR
dc.subjectE2 DNA-binding domainpt_BR
dc.subjectLI looppt_BR
dc.subjectProtein structurept_BR
dc.subject.otherPapilomavíruspt_BR
dc.titleThe structure of the extended E2 DNA-binding domain of the bovine papillomavirus-1pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1002/prot.25773pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4272-0298pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0534-481Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-5748-6863pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9496-4174pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8674-1779pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.