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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57386
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dc.creatorJoão Vitor do Carmo Barbosapt_BR
dc.creatorRodrigo Modesto Gadelha Gontijopt_BR
dc.creatorGuilherme Cavalcante de Albuquerque Souzapt_BR
dc.creatorBruno Melo Mendespt_BR
dc.creatorJuliana Batista da Silvapt_BR
dc.creatorMarcelo Mamedept_BR
dc.creatorAndréa Vidal Ferreirapt_BR
dc.date.accessioned2023-08-02T20:53:13Z-
dc.date.available2023-08-02T20:53:13Z-
dc.date.issued2021-09-20-
dc.citation.volume9pt_BR
dc.citation.issue3pt_BR
dc.citation.spage01pt_BR
dc.citation.epage19pt_BR
dc.identifier.doi10.15392/bjrs.v9i3.1734pt_BR
dc.identifier.issn23190612pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57386-
dc.description.resumoThe small animal positron emission tomography (PET) scanner from Molecular Imaging Laboratory (LIM/CDTN) is dedicated to pre-clinical studies on new 18F and 11C-based radiopharmaceuticals and to the development of novel applications for traditional radiopharmaceuticals. Quality control tests recommended by the NEMA publication NU 4-2008 are routinely carried out to ensure the proper performance of the PET scanner. The aim of this work was to evaluate the influence of image reconstruction protocols on the image quality, accuracy of attenuation and scatter correction parameters for 18F and 11C PET images. 18F-FDG and 11C-PK1122 PET images of the image quality phantom were acquired and then reconstructed using different reconstruction protocols varying algorithms (FBP, MLEM-3D, OSEM-3D), resolution mode (high/standard) and number of iterations (10 to 150). Uniformity, spill-over ratio (SOR) and recovery coefficient (RC) tests were performed for each reconstructed image according to NEMA NU 4-2008. FBP based protocol generated noisier images compared to iterative algorithms (MLEM-3D or OSEM-3D) based protocols. The increase in the number of iterations resulted in higher standard deviation of the analyzed parameters for all images. MLEM-3D and OSEM-3D based protocols generates similar results when the number of iterations and resolution mode were identical. SOR and RC mean values remained stable when the number of iterations ranged from 40 to 150. This study allowed the evaluation of different image reconstruction protocols on important parameters of 18F and 11C PET image quality. Additionally, standard protocols to be adopted in LIM/CDTN for 18F and 11C images reconstruction in preclinical studies were defined.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE ANATOMIA E IMAGEMpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofBrazilian Journal of Radiation Sciences-
dc.rightsAcesso Abertopt_BR
dc.subjectSmall Animal PETpt_BR
dc.subjectImage Qualitypt_BR
dc.subjectNEMA NU 4-2008pt_BR
dc.subject.otherTomografia por Emissão de Pósitronspt_BR
dc.subject.otherDiagnóstico por Imagempt_BR
dc.titleInfluence of image reconstruction protocols on the image quality of a small animal PET scanner using 18F and 11Cpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://bjrs.org.br/revista/index.php/REVISTA/article/view/1734pt_BR
dc.identifier.orcid0000-0001-6479-3087pt_BR
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