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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57446
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dc.creatorRosângela Maria Gomespt_BR
dc.creatorBrian Godmanpt_BR
dc.creatorFrancisco de Assis Acurciopt_BR
dc.creatorAugusto Afonso Guerra Júniorpt_BR
dc.creatorLívia Lovato Pires de Lemospt_BR
dc.creatorJuliana de Oliveira Costapt_BR
dc.creatorAlessandra Almeida Macielpt_BR
dc.creatorJuliana Alvarespt_BR
dc.creatorCharles Simão Filhopt_BR
dc.creatorMariângela Leal Cherchigliapt_BR
dc.creatorEli Iola Gurgel Andradept_BR
dc.date.accessioned2023-08-03T22:30:52Z-
dc.date.available2023-08-03T22:30:52Z-
dc.date.issued2016-
dc.citation.volume9pt_BR
dc.citation.issue7pt_BR
dc.citation.spage991pt_BR
dc.citation.epage999pt_BR
dc.identifier.doihttps://doi.org/10.1080/17512433.2016.1190270pt_BR
dc.identifier.issn1751-2433pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57446-
dc.description.resumoBackground: Cyclosporine and tacrolimus are well established immunosuppressants; however little know about long term survival rates. Aim: Compare 10-year graft survival and associated factors among kidney transplant patients within the Brazilian Public Health system (SUS) prescribed either medicine. Methods: Analyze a national cohort of kidney transplant recipients within SUS. Graft loss defined by death or dialysis for more than three months. Kaplan-Meier method used to estimate cumulative probabilities of survival. Cox proportional hazards modelused to evaluate factors associated with progression to graft loss. Results: 13,811 patients were included, 5,887 used cyclosporine and 7,924 tacrolimus. A higher risk of graft loss was associated with tacrolimus, a deceased donor, additional years of age, median period of dialysis greater than 47 months, diagnosis of diabetes as the primary cause of chronic kidney disease and transplantation between 2005 and 2009. Conclusions: Among other factors, tacrolimus based regimens were associated with worse graft survival.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofExpert Review of Clinical Pharmacology-
dc.rightsAcesso Restritopt_BR
dc.subjectKidney Transplantationpt_BR
dc.subjectsurvival analysispt_BR
dc.subjectCyclosporinept_BR
dc.subject.otherTransplante de Rimpt_BR
dc.subject.otherAnálise de Sobrevidapt_BR
dc.subject.otherCiclosporinapt_BR
dc.subject.otherEstimativa de Kaplan-Meierpt_BR
dc.titleTen-year kidney transplant survival of cyclosporine- or tacrolimus-treated patients in Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.tandfonline.com/doi/abs/10.1080/17512433.2016.1190270pt_BR
dc.identifier.orcid0000-003-4119-8925pt_BR
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