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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57551
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dc.creatorEduardo Rodrigues Fregnanipt_BR
dc.creatorThais Bianca Brandãopt_BR
dc.creatorCláudia Joffily Parahybapt_BR
dc.creatorKarina Morais Fariapt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorPedro Augusto Mendes Ramospt_BR
dc.creatorFábio Yone de Moraespt_BR
dc.creatorKarina Gondim Moutinho da Conceição Vasconcelospt_BR
dc.creatorGisela Menegussipt_BR
dc.creatorAlan Roger dos Santos Silvapt_BR
dc.date.accessioned2023-08-07T18:17:08Z-
dc.date.available2023-08-07T18:17:08Z-
dc.date.issued2016-
dc.citation.volume11pt_BR
dc.citation.issue116pt_BR
dc.citation.spage1pt_BR
dc.citation.epage9pt_BR
dc.identifier.doihttps://doi.org/10.1186/s13014-016-0694-7pt_BR
dc.identifier.issn1748-717Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57551-
dc.description.resumoBackground Radiotherapy (RT) is frequently used in the treatment of head and neck cancer, but different side-effects are frequently reported, including a higher frequency of radiation-related caries, what may be consequence of direct radiation to dental tissue. The intensity-modulated radiotherapy (IMRT) was developed to improve tumor control and decrease patient’s morbidity by delivering radiation beams only to tumor shapes and sparing normal tissue. However, teeth are usually not included in IMRT plannings and the real efficacy of IMRT in the dental context has not been addressed. Therefore, the aim of this study is to assess whether IMRT delivers lower radiation doses to dental structures than conformal 3D radiotherapy (3DRT). Material and methods Radiation dose delivery to dental structures of 80 patients treated for head and neck cancers (oral cavity, tongue, nasopharynx and oropharynx) with IMRT (40 patients) and 3DRT (40 patients) were assessed by individually contouring tooth crowns on patients’ treatment plans. Clinicopathological data were retrieved from patients’ medical files. Results The average dose of radiation to teeth delivered by IMRT was significantly lower than with 3DRT (p = 0.007); however, only patients affected by nasopharynx and oral cavity cancers demonstrated significantly lower doses with IMRT (p = 0.012 and p = 0.011, respectively). Molars received more radiation with both 3DRT and IMRT, but the latter delivered significantly lower radiation in this group of teeth (p < 0.001), whereas no significant difference was found for the other dental groups. Maxillary teeth received lower doses than mandibular teeth, but only IMRT delivered significantly lower doses (p = 0.011 and p = 0.003). Ipsilateral teeth received higher doses than contralateral teeth with both techniques and IMRT delivered significantly lower radiation than 3DRT for contralateral dental structures (p < 0.001). Conclusion IMRT delivered lower radiation doses to teeth than 3DRT, but only for some groups of patients and teeth, suggesting that this decrease was more likely due to the protection of other high risk organs, and was not enough to remove teeth from the zone of high risk for radiogenic disturbance (>30Gy).pt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRadiation Oncologypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectIntensity-modulated radiotherapypt_BR
dc.subject3D radiotherapypt_BR
dc.subjectHead and neck cancerpt_BR
dc.subjectTeethpt_BR
dc.subjectDental structurespt_BR
dc.subject.otherRadioterapiapt_BR
dc.subject.otherDentespt_BR
dc.subject.otherCabeça - Câncerpt_BR
dc.subject.otherPescoço - Câncerpt_BR
dc.titleIMRT delivers lower radiation doses to dental structures than 3DRT in head and neck cancer patientspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://ro-journal.biomedcentral.com/articles/10.1186/s13014-016-0694-7#:~:text=Conclusion,radiogenic%20disturbance%20(%3E30Gy).pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-5196-7631pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9128-3138pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4835-9624pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6657-4547pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9544-6555pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8410-4303pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2040-6617pt_BR
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