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http://hdl.handle.net/1843/57665| Tipo: | Artigo de Periódico |
| Título: | Extracapsular extension and tumor implants in lymph nodes with canine mammary carcinoma metastasis: Study of the impact on survival |
| Autor(es): | Aline De B. Bassani Gonçalves T. C. Reis de Pinho F. A. O. Toledo Débora Balabram Ênio Ferreira Marina Rios de Araújo Campos Geovanni Dantas Cassali |
| Resumen: | Regional lymph node status impacts survival in dogs with malignant mammary tumors. However, few studies have evaluated extracapsular extension and tumor implants in regional lymph node metastases in dogs with mammary carcinoma. Therefore, 84 cases of mammary carcinomas with metastases in inguinal and/or axillary lymph nodes from female dogs of different breeds and a total of 139 metastatic lymph nodes were evaluated by routine histological staining. Clinical and pathological characteristics of primary tumors as well as the presence of extracapsular extension and tumor implants in the lymph nodes were analyzed, in addition to survival. One to 5 lymph nodes were evaluated in each case. Extracapsular extension and tumor implants were present in 17.9% and 39.3% of cases, respectively. The simultaneous presence of extracapsular extension and tumor implants were associated with an increased risk of death (hazard ratio 10.46). In addition, “special type carcinomas”, high histological grade (grade III), and presence of extracapsular extension associated with tumor implants were related to a worse prognosis and shorter survival times (p < 0.05). Based on these results, we highlight the importance of identifying extracapsular extension and tumor implants in dogs with metastatic mammary carcinomas, as they are associated with a higher risk of death and shorter survival |
| Asunto: | Neoplasias Mamárias Animais Cães Metástase Linfática Extensão Extranodal |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Institución: | UFMG |
| Departamento: | ICB - DEPARTAMENTO DE PATOLOGIA MED - DEPARTAMENTO DE CIRURGIA |
| Tipo de acceso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1016/j.rvsc.2021.07.010 |
| URI: | http://hdl.handle.net/1843/57665 |
| Fecha del documento: | 5-jul-2021 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0034528821002241?via%3Dihub |
| metadata.dc.relation.ispartof: | Research in Veterinary Science |
| Aparece en las colecciones: | Artigo de Periódico |
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