1. Repositório Institucional da UFMG
2. Publicações Científicas e Culturais
3. Artigo de Periódico

Tipo:	Artigo de Periódico
Título:	Challenges for the Implementation of the First Large-Scale Rheumatic Heart Disease Screening Program in Brazil: The PROVAR Study Experience
Autor(es):	Julia Pereira Afonso Dos Santos Gabriel Assis Lopes do Carmo Andrea Zawacki Beaton Tainá Vitti Lourenço Adriana Costa Diamantino Maria do Carmo Pereira Nunes Craig Sable Bruno Ramos Nascimento
Resumen:	Rheumatic Heart Disease (RHD) is the cardiac consequence of acute rheumatic fever (ARF), an inflammatory disease triggered by streptococcal pharyngitis. Although the prevalence of RHD has decreased in high-income countries, lack of social and economic development and poor primary prevention – mainly in in low- and middle-income countries – perpetuate an environment where RHD remains endemic. It is estimated that RHD continues to affect nearly 33 million people worldwide.1 According to the World Health Organization (WHO), RHD is responsible for 1-1.5% of all cardiovascular deaths and 3-4% of cardiovascular Disability-Adjusted Life Years (DALYs).2 In Brazil, according to the Unified Health System (SUS), there were 26,054 hospital admissions for ARF (45% with cardiac compromise) between 2008 and 2015, and the total cost to SUS was US$3.5 million, a number that is most likely underestimated.3 The main burden of RHD to public health systems consists of repeated hospital admissions and cardiac surgeries in the following decades after initial cardiac damage. If RHD is detected in its early stages, secondary prophylaxis (regular penicillin injections) can be initiated to prevent new episodes of ARF, avoiding further valve damage and progression of RHD. In high prevalence regions, RHD meets the traditional screening criteria defined by Wilson and Jungner,4 although the long-term clinical significance of latent RHD is not entirely clear. Previous studies have demonstrated, however, that in 38 to 68% of asymptomatic RHD patients, echocardiographic findings show that abnormalities persist, and progress in 4 to 16%,5 reinforcing the importance of early diagnosis in susceptible populations.The PROVAR study (Programa de Rastreamento da Valvopatia Reumática – Rheumatic Heart Disease Screening Program) is the first large-scale echocardiographic screening program in Brazil, using echocardiography to estimate the prevalence of latent RHD in asymptomatic children between 5 and 18 years old attending public schools of underserved areas of the cities Belo Horizonte, Montes Claros and Bocaiúva, in the Brazilian State of Minas Gerais. Minas Gerais is the second most populous Brazilian state (>20 million inhabitants) and has a large territory, great geographical diversity and is marked by economic discrepancies between its different regions. This project is a clinical and research collaboration between the University Hospital of Universidade Federal de Minas Gerais (UFMG), Brazil, and the Children’s National Health System (CNHS) in Washington DC, United States of America (USA).
Asunto:	Cardiopatia Reumática Programas de Rastreamento Echocardiography Saúde da criança Saúde do Adolescente
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Institución:	UFMG
Departamento:	MED - DEPARTAMENTO DE CLÍNICA MÉDICA
Tipo de acceso:	Acesso Aberto
Identificador DOI:	10.5935/abc.20170047
URI:	http://hdl.handle.net/1843/57822
Fecha del documento:	2017
metadata.dc.url.externa:	https://www.scielo.br/j/abc/a/yzqNHCsknnhVT4wjjsKMKsv/?lang=en
metadata.dc.relation.ispartof:	Arquivos Brasileiros de Cardiologia
Aparece en las colecciones:	Artigo de Periódico

Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.