Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/57951
Type: | Artigo de Periódico |
Title: | Zika virus challenges for neuropsychiatry |
Authors: | Ana Cristina Simões e Silva Janaina Matos Moreira Roberta Maia Castro Rmanelli Antônio Lúcio Teixeira |
Abstract: | Before 2007, Zika virus (ZIKV) was generally considered as an arbovirus of low clinical relevance, causing a mild self-limiting febrile illness in tropical Africa and Southeast Asia. Currently, a large, ongoing outbreak of ZIKV that started in Brazil in 2015 is spreading across the Americas. Virus infection during pregnancy has been potentially linked to congenital malformations, including microcephaly. In addition to congenital malformations, a temporal association between ZIKV infection and an increase in cases of Guillain–Barré syndrome is currently being observed in several countries. The mechanisms underlying these neurological complications are still unknown. Emerging evidence, mainly from in vitro studies, suggests that ZIKV may have direct effects on neuronal cells. The aim of this study was to critically review the literature available regarding the neurobiology of ZIKV and its potential neuropsychiatric manifestations. |
Subject: | Zika virus Síndrome de Guillain-Barré Microcefalia Transtornos do Neurodesenvolvimento |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | MED - DEPARTAMENTO DE PEDIATRIA |
Rights: | Acesso Aberto |
metadata.dc.identifier.doi: | 10.2147/NDT.S113037 |
URI: | http://hdl.handle.net/1843/57951 |
Issue Date: | 2016 |
metadata.dc.url.externa: | https://www.dovepress.com/zika-virus-challenges-for-neuropsychiatry-peer-reviewed-fulltext-article-NDT |
metadata.dc.relation.ispartof: | Neuropsychiatric Disease and Treatment |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Zika virus challenges for neuropsychiatry pdfa.pdf | 235.05 kB | Adobe PDF | View/Open |
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