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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/58093
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dc.creatorShankargouda Patilpt_BR
dc.creatorGururaj Arakeript_BR
dc.creatorAbdul Wahab Alamirpt_BR
dc.creatorShekhar Patilpt_BR
dc.creatorKamran Habib Awanpt_BR
dc.creatorHosam Baeshenpt_BR
dc.creatorThirumal Rajpt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorPeter a. Brennanpt_BR
dc.date.accessioned2023-08-22T20:26:45Z-
dc.date.available2023-08-22T20:26:45Z-
dc.date.issued2020-
dc.citation.volume49pt_BR
dc.citation.spage102pt_BR
dc.citation.epage109pt_BR
dc.identifier.doihttps://doi.org/10.1111/jop.12954pt_BR
dc.identifier.issn0904-2512pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/58093-
dc.description.resumoIntroduction: Toombak is a form of smokeless tobacco that is not well known in Western Society but is widely used by the Sudanese population and many others in the sub‐Sahara region. However, unlike other smokeless tobacco products, information on the carcinogenic potential of toombak is scarce. The present review explored any potential epidemiological association between the use of toombak and oral leukoplakia and oral squamous cell carcinoma (OSCC). Methods: Databases including the Web of Science, SCOPUS, EMBASE and PubMed were searched for literature on the potential association between toombak and oral leukoplakia and OSCC. The search also included grey literature. The search period extended from 1990 to 2018. Following data mining, the study selection was conducted by two reviewers independently. Results: Eight studies that satisfied the inclusion criteria were included. Based on these results, there was a threefoldto sevenfold increased risk of developing the oral leukoplakia and oral squamous cell carcinoma among toombak users compared with non‐users. Conclusion: Based on the results of the systematic review, there is a strong epidemiological evidence to suggest toombak to be a major risk factor for both oral leukoplakia and OSCC. Further studies are necessary to evaluate the molecular pathway of toombak‐induced oral carcinogenesis.pt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Oral Pathology & Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectOral cancerpt_BR
dc.subjectOral luekoplakiapt_BR
dc.subjectOral squamous cell carcinomapt_BR
dc.subjectSmokeless tobaccopt_BR
dc.subjectSudanpt_BR
dc.subjectSystematic reviewpt_BR
dc.subjectToombakpt_BR
dc.subject.otherBoca - Câncerpt_BR
dc.subject.otherLeucoplasia bucalpt_BR
dc.titleIs toombak a risk factor for oral leukoplakia and oral squamous cell carcinoma? A systematic reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12954pt_BR
dc.identifier.orcidhttps://orcid.org/0009-0008-3588-6178pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2032-4526pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1979-0263pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8323-2282pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3831-7455pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1079-1024pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6657-4547pt_BR
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