Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59011
Type: Artigo de Periódico
Title: Association between consumption of ultra-processed foods and serum c-reactive protein levels: cross-sectional results from the elsa-brasil study
Authors: Aline Ester da Silva Cruzlopes
Larissa Fortunato Araújo
Renata Bertazzi Levy
Sandhi Maria Barreto
Luana Giatti Gonçalves
Abstract: BACKGROUND: There may be a direct association between consumption of ultra-processed foods and C-reactive protein (CRP) levels, under the assumption that the high glycemic index of these food products could stimulate the entire chronic inflammation cascade, along with an indirect association mediated by obesity. The types of food consumed, including ultra-processed products, strongly influence obesity, and are also associated with higher serum CRP levels.OBJECTIVE: Our aim was to investigate whether the caloric contribution of ultra-processed foods to diet is associated with CRP levels, independent of body mass index (BMI). DESIGN AND SETTING: Cross-sectional analysis on the Longitudinal Study of Adult Health (ELSA-Brasil) baseline cohort (2008-2010). METHODS: Dietary information, obtained through a food frequency questionnaire, was used to estimate the percentage of energy contribution from ultra-processed food to individuals’ total caloric intake. CRP levels were the response variable. Sex-specific associations were estimated using generalized linear models with gamma distribution and log-link function. RESULTS: Ultra-processed food accounted for 20% of total energy intake. Among men, after adjustments for sociodemographic characteristics, there was no association between ultra-processed food intake and CRP levels. Among women, after adjustment for sociodemographic characteristics, smoking and physical activity, the highest tercile of ultra-processed food intake was associated with mean CRP levels that were 14% higher (95% confidence interval: 1.04-1.24) than those of the lowest tercile. However, after considering BMI, this association lost statistical significance. CONCLUSION: Our findings suggest that the positive association of ultra-processed food consumption with CRP levels among women seems to be mediated by the presence of adiposity
Subject: Diet Therapy
C-Reactive Protein
Inflammation
Obesity
Cross-Sectional Studies
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: MED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIAL
Rights: Acesso Aberto
metadata.dc.identifier.doi: 10.1590/1516-3180.2018.0363070219
URI: http://hdl.handle.net/1843/59011
Issue Date: 7-Feb-2019
metadata.dc.url.externa: https://pubmed.ncbi.nlm.nih.gov/31314878/
metadata.dc.relation.ispartof: Sao Paulo Medical Journal
Appears in Collections:Artigo de Periódico

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