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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59072
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dc.creatorAndre Soares Santospt_BR
dc.creatorKenya Valeria Micaela de Souza Noronhapt_BR
dc.creatorMonica Viegas Andradept_BR
dc.date.accessioned2023-10-02T20:38:03Z-
dc.date.available2023-10-02T20:38:03Z-
dc.date.issued2019-
dc.citation.volume124pt_BR
dc.citation.issue1pt_BR
dc.citation.spagee1pt_BR
dc.citation.epagee16pt_BR
dc.identifier.doi10.1016/j.bja.2019.09.017pt_BR
dc.identifier.issn0007-0912pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59072-
dc.description.resumoThe meta-analysis by Serraino and Murphy1 on viscoelastic haemostatic assays (VHA) for the diagnosis and treatment of coagulopathic bleeding in cardiac surgery and subsequent comments2,3 suggest some uncertainty around the association between transfusion of allogeneic red blood cells, fresh frozen plasma, and platelets and final outcomes, as discussed.1 Kozek and colleagues2 made two arguments using final outcomes to justify their support of VHA: (i) the observed risk reduction in acute renal failure reported by Serraino and Murphy1 (odds ratio [OR]=0.42, 95% confidence interval [CI]=0.20–0.86; P=0.02; four studies, 424 patients; data taken from supplementary materials provided by the authors) and (ii) the risk reduction in mortality reported by Wikkelsø and colleagues4,5 (3.9% vs 7.4%; relative risk [RR]=0.52, 95% CI=0.28–0.95; P=0.033, not specific for cardiac patients). We agree that the reduction of the risk of acute renal failure is an important outcome, but the mortality reduction reported by Wikkelsø and colleagues4,5 was found through a fixed-effects model combining data from different populations. Heterogeneity was null, but a random-effects model (REM) would be advised regardless.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFCE - DEPARTAMENTO DE CIÊNCIAS ECONÔMICASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofBritish Journal of Anaesthesia-
dc.rightsAcesso Abertopt_BR
dc.subjectBleedingpt_BR
dc.subjectCoagulopathypt_BR
dc.subjectPoint of care testingpt_BR
dc.subjectTransfusionpt_BR
dc.subjectViscoelastic blood testconcentrationpt_BR
dc.subject.otherCirurgia cardiacapt_BR
dc.subject.otherCoagulacaopt_BR
dc.subject.otherTransfusão de componentes sanguineospt_BR
dc.titleRoutine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgerypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.bjanaesthesia.org/article/S0007-0912(19)30697-X/fulltextpt_BR
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