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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59491
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dc.creatorIsaac de F. Corradipt_BR
dc.creatorEdward de Souzapt_BR
dc.creatorDenise Sandept_BR
dc.creatorJacqueline Aparecida Takahashipt_BR
dc.date.accessioned2023-10-16T21:45:43Z-
dc.date.available2023-10-16T21:45:43Z-
dc.date.issued2018-
dc.citation.volume64pt_BR
dc.citation.spage109pt_BR
dc.citation.epage114pt_BR
dc.identifier.doihttps://doi.org/10.3303/CET1864019pt_BR
dc.identifier.issn2283-9216pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59491-
dc.description.resumoPlants are a natural source of strategic bio-active chemicals able to inhibit tyrosinase and reduce reactive oxygen species helping to protect human body against diseases related to alterations in DNA and cancer. Anti-tyrosinase and antioxidant compounds are widely commercialized as components in foods, as well as in other products from pharmaceutical, cosmetics and health industries. Searching for plants containing natural antioxidants and bioactive compounds, we described a preliminary study in which eighteen extracts from thirteen plant species showed an interesting anti-tyrosinase potential. Schinus terebinthifolius was one of the most interesting plant species detected in the previous study. In this way, the present work aimed to evaluate the correlation between phenolic compounds contents and biological activities (anti-tyrosinase and antioxidant) of different extracts from S. terebinthifolius (barks and leaves). HPLC profile and antioxidant activities were determined for the extracts. Some secondary metabolites (caffeic and gallic acids as well as methyl gallate) were identified via HPLC and spectroscopic methods in S. terebinthifolius extracts. The in vitro anti-tyrosinase activity of these compounds was also evaluated and the extension of their activity was compared to the anti-tyrosinase activity of the crude extracts. Gallic and caffeic acid were found in both leaves and bark extracts. Gallic acid showed low anti-tyrosinase activity (30 %), in its pure form, but its presence was positively associated with improved degrees of anti-tyrosinase (69-75 %) and antioxidant activities (inhibition concentration – IC) of the extracts (IC 50 % ABTS: 16.6 - 23.9 µg.mL-1 and IC 50 % DPPH: 295.2 – 392.4 µg.mL-1). Schinus terebinthifolius extracts are, therefore, promising natural source of tyrosinase inhibitors (in bark extracts) and antioxidant agents (especially in leaves extracts), showing biotechnological potential to be used as functional food, nutraceutical or in cosmetic formulations.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofChemical Engineering Transactionspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAntioxidantespt_BR
dc.subjectQuímicapt_BR
dc.subject.otherAntioxidantespt_BR
dc.subject.otherQuímicapt_BR
dc.titleCorrelation Between Phenolic Compounds Contents, Anti-tyrosinase and Antioxidant Activities of Plant Extractspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.aidic.it/cet/18/64/019.pdfpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8831-1609pt_BR
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