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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59675
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dc.creatorAdrianne Maria Berno Rezende Duartept_BR
dc.creatorJosé de Bessapt_BR
dc.creatorFlavia Cristina de Carvalho Mradpt_BR
dc.creatorSandra Helena Cerrato Tibiriçapt_BR
dc.creatorMaira Camargopt_BR
dc.creatorAugusto Alves Pinho Vieirapt_BR
dc.creatorFrederico Cantarino Cordeiro Araujopt_BR
dc.creatorAndré Avarese de Figueiredopt_BR
dc.creatorJose Murillo Bastos Nettopt_BR
dc.date.accessioned2023-10-18T21:18:33Z-
dc.date.available2023-10-18T21:18:33Z-
dc.date.issued2017-
dc.citation.volume63pt_BR
dc.citation.issue8pt_BR
dc.citation.spage693pt_BR
dc.citation.epage696pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/1806-9282.63.08.693pt_BR
dc.identifier.issn01044230pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59675-
dc.description.resumoIntroduction: Cryptorchidism is a common and prevalent condition in patients with Down syndrome. Environmental factors, such as smoking, can be associated with malformations during fetal development. The study of the prevalence of cryptorchidism and its association with parental tobacco use in Down syndrome can contribute to alert health care professionals, patients and family members regarding the prevention of the harms caused by cryptorchidism and its possible predisposing factors. Objective: To evaluate the prevalence of cryptorchidism in Down syndrome and its association with maternal and paternal smoking.Method: Forty (40) patients of a public clinic specialized in Down syndrome were evaluated, using a semi-structured questionnaire for evaluation of antecedents and sociodemographic characteristics, as well as physical and complementary examinations.Results: Cryptorchidism was observed in 27.5% of the patients (95CI 15.98-42.96). Of these, 55% (5/9) were the children of mothers who smoked during pregnancy, and 19.35% (6/31) were the children of mothers who did not smoke during pregnancy (OR = 5.26 [95CI 1.06-25.41]; p=0.032). Similarly, paternal smoking was also observed in greater frequency among the parents of cryptorchid patients compared with subjects with descended testis, 63.36% (7/11) and 31.03% (9/29), respectively (OR = 3.89 [95CI 0.91-16.73]; p=0.060).Conclusion: The prevalence of cryptorchidism is high in patients with Down syndrome. We can show a strong association between smoking parents and the occurrence of cryptorchidism, especially when it comes to maternal smoking.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRevista da Associação Médica Brasileira-
dc.rightsAcesso Abertopt_BR
dc.subjectSmokingpt_BR
dc.subjectDown syndromept_BR
dc.subjectCryptorchidismpt_BR
dc.subjectUrologic diseasespt_BR
dc.subject.otherSmokingpt_BR
dc.subject.otherDown syndromept_BR
dc.subject.otherCryptorchidismpt_BR
dc.subject.otherUrologic diseasespt_BR
dc.titleSmoking and its association with cryptorchidism in down syndromept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttp://dx.doi.org/10.1590/1806-9282.63.08.693pt_BR
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