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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59854
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dc.creatorGururaj Arakeript_BR
dc.creatorMatthias Merkxpt_BR
dc.creatorPeter Brennanpt_BR
dc.creatorDeepak Thomaspt_BR
dc.creatorAbdulsalam Aljababpt_BR
dc.creatorSantosh Hunasgipt_BR
dc.creatorKirthi Kumar Raipt_BR
dc.creatorBeverley Halept_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorRicardo Santiago Gomezpt_BR
dc.creatorSiavash Rahimipt_BR
dc.date.accessioned2023-10-23T20:47:44Z-
dc.date.available2023-10-23T20:47:44Z-
dc.date.issued2018-
dc.citation.volume47pt_BR
dc.citation.issue4pt_BR
dc.citation.spage403pt_BR
dc.citation.epage409pt_BR
dc.identifier.doihttps://doi.org/10.1111/jop.12689pt_BR
dc.identifier.issn09042512pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59854-
dc.description.resumoBackground: We have evaluated the rationale of existing grading and staging schemes of oral submucous fibrosis (OSMF) based on how they are categorized. A novel classification and staging scheme is proposed. Methods: A total of 300 OSMF patients were evaluated for agreement between functional, clinical, and histopathological staging. Bilateral biopsies were assessed in 25 patients to evaluate for any differences in histopathological staging of OSMF in the same mouth. Extent of clinician agreement for categorized staging data was evaluated using Cohen's weighted kappa analysis. Cross-tabulation was performed on categorical grading data to understand the intercorrelation, and the unweighted kappa analysis was used to assess the bilateral grade agreement. Probabilities of less than 0.05 were considered significant. Data were analyzed using SPSS Statistics (version 25.0, IBM, USA). Results: A low agreement was found between all the stages depicting the independent nature of trismus, clinical features, and histopathological components (K = 0.312, 0.167, 0.152) in OSMF. Following analysis, a three-component classification scheme (TFM classification) was developed that describes the severity of each independently, grouping them using a novel three-tier staging scheme as a guide to the treatment plan. Conclusion: The proposed classification and staging could be useful for effective communication, categorization, and for recording data and prognosis, and for guiding treatment plans. Furthermore, the classification considers OSMF malignant transformation in detail.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Oral Pathology & Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectcarcinoma de células escamosas de bocapt_BR
dc.subjectcâncer de cabeça e pescoçopt_BR
dc.subjectneoplasias de cabeça e pescoçopt_BR
dc.subjectbusca 09 do 09 2023 assunto oral submucous fibrosis oral submucous fibrosis fao clinicapt_BR
dc.subject.otherOral submucous fibrosispt_BR
dc.subject.otherClassificationpt_BR
dc.titleTfm classification and staging of oral submucous fibrosis: a new proposalpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12689pt_BR
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