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http://hdl.handle.net/1843/60192| Type: | Artigo de Periódico |
| Title: | Phylogenomics and gene selection in Aspergillus welwitschiae: Possible implications in the pathogenicity in Agave sisalana |
| Authors: | Gabriel Quintanilha-Peixoto Daniel S. Araújo Ruth B. De-Paula Elizabeth A. A. Duarte Fernanda Badotti Vasco Ariston de Carvalho Azevedo Bertram Brenig Ana Cristina Fermino Soares Marcelo Falsarella Carazzolle Aristóteles Góes Neto Marina Püpke Marone Fábio Trigo Raya Juliana José Adriele Oliveira Paula Luize Camargos Fonseca Luiz Marcelo Ribeiro Tomé Dener Eduardo Bortolini Rodrigo Bentes Kato |
| Abstract: | Aspergillus welwitschiae causes bole rot disease in sisal (Agave sisalana and related species) which affects the production of natural fibers in Brazil, the main worldwide producer of sisal fibers. This fungus is a saprotroph with a broad host range. Previous research established A. welwitschiae as the only causative agent of bole rot in the field, but little is known about the evolution of this species and its strains. In this work, we performed a comparative genomics analysis of 40 Aspergillus strains. We show the conflicting molecular identity of this species, with one sisal-infecting strain sharing its last common ancestor with Aspergillus niger, having diverged only 833 thousand years ago. Furthermore, our analysis of positive selection reveals sites under selection in genes coding for siderophore transporters, Sodium‑calcium exchangers, and Phosphatidylethanolamine-binding proteins (PEBPs). Herein, we discuss the possible impacts of these gene functions on the pathogenicity in sisal. |
| Subject: | Sideróforos Genes Microorganismos patogênicos |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICB - DEPARTAMENTO DE MICROBIOLOGIA ICB - INSTITUTO DE CIÊNCIAS BIOLOGICAS |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.ygeno.2022.110517 |
| URI: | http://hdl.handle.net/1843/60192 |
| Issue Date: | Nov-2022 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0888754322002622?via%3Dihub |
| metadata.dc.relation.ispartof: | Genomics |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Phylogenomics and gene selection in Aspergillus welwitschiae_ Possible implications in the pathogenicity in Agave sisalana.pdf | 29.64 MB | Adobe PDF | View/Open |
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