1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60232
Full metadata record
DC FieldValueLanguage
dc.creatorErika Vivian Santospt_BR
dc.creatorRodrigo Lima Domingospt_BR
dc.creatorIdael Mateus Goes Lopespt_BR
dc.creatorLis Lorena Melúcio Guedespt_BR
dc.creatorValesca Ribeiro Limapt_BR
dc.creatorLarissa Alves Cardosopt_BR
dc.creatorBruno Alexander Nunes Silvapt_BR
dc.creatorDalton de Oliveira Fontespt_BR
dc.creatorMara da Silveira Benfatopt_BR
dc.creatorFernanda Schäfer Hackenhaarpt_BR
dc.creatorTiago Salomonpt_BR
dc.creatorDavid Vani Jacobpt_BR
dc.creatorDamien Prévéraudpt_BR
dc.creatorWagner Azis Garcia Araujopt_BR
dc.creatorEduardo Maria da Glóriapt_BR
dc.date.accessioned2023-10-30T14:56:54Z-
dc.date.available2023-10-30T14:56:54Z-
dc.date.issued2021-
dc.citation.volume99pt_BR
dc.citation.issue10pt_BR
dc.citation.spage5647pt_BR
dc.citation.epage5652pt_BR
dc.identifier.doihttps://doi.org/10.1093/jas/skab329pt_BR
dc.identifier.issn1525-3163pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60232-
dc.description.resumoIngestion of mycotoxins can result in many problems, including decreased growth rates and immune suppression. The present study aimed to evaluate the impact of the supplementation of a mycotoxin deactivator composed by adsorbent clay minerals; inactivated fermentation extracts of Saccharomyces cerevisiae; and blend of antioxidants, organic acids, and botanicals in diets containing added mycotoxins for nursery pigs on their performance and antioxidant status. Ninety pigs weaned with 24 d of age (7.12 ± 0.68 kg of BW) were used. Pigs were housed in pens of three animals each according to body weight, litter origin, and sex. The dietary treatments consisted of feeding the pigs with a standard control diet as negative control (NC; mycotoxin levels at accepted regulatory Brazilian Ministry of Agriculture standards; deoxynivalenol (DON): <100 μg/kg; zearalenone (ZEA): <20 μg/kg; fumonisins (FB): <1 mg/kg); the standard diet added with mycotoxins to reach a low contamination level is considered as positive low (PCL−; DON: 900 μg/kg; ZEA: 100 μg/kg; FB: 5,000 μg/kg) without deactivator; a positive low added the deactivator at an inclusion rate of 1 kg/ton (PCL+); the standard diet added with mycotoxins to reach a high contamination level is considered as positive high (PCH−; DON: 4,500 μg/kg; ZEA: 500 μg/kg; FB: 18,000 μg/kg) without the deactivator; and a positive high added the deactivator at an inclusion rate of 5 kg/ton (PCH+). Pigs were individually weighed at the beginning and at the end of each phase and feed intake recorded based on daily pen intake during the experiment. On days 7, 19, 34, and 43 post-weaning, blood samples were drawn for antioxidant analyses. Antioxidant enzymes (glutathione peroxidase [GPx] and total superoxide dismutase [TSOD]), vitamins [Vit A, E, and C], and malondialdehyde [MDA]) were evaluated in erythrocyte and plasma samples. Pigs challenged with mycotoxins presented lower performance traits, decrease in the efficiency of central antioxidant systems (↓GPx, ↓TSOD, ↓Vit A, ↓Vit E, and ↓Vit C), and a higher oxidative damage to lipids (↑MDA) when compared with the control and deactivator-associated treatments. Our findings showed that the use of a mycotoxin deactivator can mitigate the negative impacts on performance and oxidative stress when animals are subjected to diets contaminated by different levels of mycotoxins.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Animal Science-
dc.rightsAcesso Restritopt_BR
dc.subject.otherSuíno -- Criaçãopt_BR
dc.subject.otherNutrição animalpt_BR
dc.subject.otherAlimentação e raçõespt_BR
dc.subject.otherSuíno -- Desempenhopt_BR
dc.subject.otherToxicologiapt_BR
dc.titleMycotoxin deactivator improves performance, antioxidant status, and reduces oxidative stress in nursery pigs fed diets containing mycotoxinspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://academic.oup.com/jas/article-abstract/99/10/skab277/6380201pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.