Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60254
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dc.creatorBruno Marizpt_BR
dc.creatorCiro Dantas Soarespt_BR
dc.creatorThayna Melo de Lima Moraispt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorMaria Goreti Carvalhopt_BR
dc.creatorJacks Jorge Juniorpt_BR
dc.date.accessioned2023-10-30T18:06:13Z-
dc.date.available2023-10-30T18:06:13Z-
dc.date.issued2018-
dc.citation.volume47pt_BR
dc.citation.issue9pt_BR
dc.citation.spage816pt_BR
dc.citation.epage822pt_BR
dc.identifier.doihttps://doi.org/10.1111/jop.12773pt_BR
dc.identifier.issn09042512pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60254-
dc.description.resumoFibroblast growth factor 2 (FGF-2) is a multifunctional cytokine expressed in several tissues and involved in a wide variety of biologic activities, with one low molecular weight (LMW) protein present in the cytosol, which is secreted, acting via its receptors (FGFRs), and four high molecular weight (HMW) proteins located in the nucleus. Fibroblast growth factor receptor (FGFR) family has four (FGFR1-4) transmembrane tyrosine kinase receptors expressed on several cell types, and FGFR-1 has been indicated as a potential molecular target in several types of cancer, including oral squamous cell carcinoma (OSCC). The FGF-2/FGFR-1 expression has been studied in the oral cavity, and it was associated with the wound repair process, the development of benign and malignant salivary gland tumors, besides being related to oral potentially malignant disorders (OPMDs) and OSCC. Hence, we critically review the currently available data on FGF-2/FGFR-1 expression in the normal mucosa and lesions of the oral cavitypt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Oral Pathology & Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectacesso restrito assunto Fibroblast Growth Factor 2 fao clinica busca dia 15 do 09 2023 assuntopt_BR
dc.subject.otherFibroblast growth factorspt_BR
dc.subject.otherProtein-Tyrosine Kinasespt_BR
dc.subject.otherFibroblast growth factor 2pt_BR
dc.subject.otherFibroblast growth factor 1pt_BR
dc.subject.otherProteinspt_BR
dc.subject.otherCarcinomapt_BR
dc.subject.otherMouth neoplasmspt_BR
dc.titleExpression of FGF-2/FGFR-1 in normal mucosa, salivary gland, preneoplastic, and neoplastic lesions of the oral cavitypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12773pt_BR
Appears in Collections:Artigo de Periódico

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