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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60504
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dc.creatorBianca F.nicolosipt_BR
dc.creatorPhilip n. Bakerpt_BR
dc.creatorLouise c. Kennypt_BR
dc.creatorJose g. Cecattipt_BR
dc.creatorIracema m. Calderonpt_BR
dc.creatorRenato t. Souzapt_BR
dc.creatorJussara de Souza Mayrink Novaispt_BR
dc.creatorFrancisco e. Feitosapt_BR
dc.creatorEdilberto a. Rocha Filhopt_BR
dc.creatorDébora f. Leitept_BR
dc.creatorJanete Vettorazzipt_BR
dc.creatorMaria h. Sousapt_BR
dc.creatorMaria l. Costapt_BR
dc.date.accessioned2023-11-06T19:52:51Z-
dc.date.available2023-11-06T19:52:51Z-
dc.date.issued2020-
dc.citation.volume15pt_BR
dc.citation.spage1pt_BR
dc.citation.epage14pt_BR
dc.identifier.doi10.1371/journal.pone.0232664pt_BR
dc.identifier.issn19326203pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60504-
dc.description.resumoObjective:To assess the incidence and risk factors for hyperglycemia in pregnancy in a cohort of Bra zilian nulliparous pregnant women.Materials and methods:This is a secondary analysis of a multicenter cohort study that enrolled 1,008 nulliparous pregnant women at 19–21 weeks. Exclusion criteria included chronic exposure to corticosteroids and previous diabetes. Bivariate and multivariate analyses by Poisson regression were used to identify associated factors.Results:The incidence of hyperglycemia in pregnancy was 14.9% (150/1,008), and 94.7% of these cases were gestational diabetes mellitus (142/150). Significant associated factors included a family history of diabetes mellitus, maternal overweight or obesity at enrollment, and previous maternal conditions (polycystic ovarian syndrome, thyroid dysfunctions and hypertensive disorders). A BMI 26.3Kg/m2(RRadj 1.87 [1.66–2.10]) and a family history of diabetes mellitus (RRadj 1.71 [1.37–2.15]) at enrollment were independent risk factors for HIP.Conclusions: A family history of diabetes mellitus and overweight or obesity (until 19–21 weeks of gestation) may be used as selective markers for HIP in Brazilian nulliparous women. Given the carcity of results in nulliparous women, our findings may contribute to determine the optimal diagnostic approach in populations of similar socioeconomic characteristics.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPLoS One-
dc.rightsAcesso Abertopt_BR
dc.subjectHyperglycemiapt_BR
dc.subjectPregnancypt_BR
dc.subjectDiabetes, Gestationalpt_BR
dc.subject.otherHyperglycemiapt_BR
dc.subject.otherPregnancypt_BR
dc.subject.otherDiabetes, Gestationalpt_BR
dc.titleIncidence and risk factors for hyperglycemia in pregnancy among nulliparous women: a brazilian multicenter cohort studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://pubmed.ncbi.nlm.nih.gov/32401767/pt_BR
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