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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60526
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dc.creatorFlávia Sirotheau Corrêa Pontespt_BR
dc.creatorJonas Ikikame de Oliveirapt_BR
dc.creatorLucas Lacerda de Souzapt_BR
dc.creatorOslei Paes de Almeidapt_BR
dc.creatorEduardo Rodrigues Fregnanipt_BR
dc.creatorRafael Sarlo Vilelapt_BR
dc.creatorWanessa Miranda-Silvapt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorHélder Antônio Rebelo Pontespt_BR
dc.date.accessioned2023-11-06T20:46:16Z-
dc.date.available2023-11-06T20:46:16Z-
dc.date.issued2018-02-25-
dc.citation.issue2pt_BR
dc.citation.spagee188pt_BR
dc.citation.epagee197pt_BR
dc.identifier.doihttps://doi.org/10.4317%2Fmedoral.22106pt_BR
dc.identifier.issn16986946pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60526-
dc.description.resumoBackground To describe the clinicopathological characteristics of a series of head and neck rhabdomyosarcoma (RMS) and to review the literature. Material and Methods Cases diagnosed as RMS affecting the head and neck region were retrospectively retrieved from the files of two Brazilian institutions from January 2006 to January 2017. Data on clinical features (sex, age and affected site), microscopic subtype, immunohistochemical results, treatment employed and follow-up status were obtained from the patient’s medical charts. Results During the period considered, 10 cases of RMS were identified. Females predominated (4M:6F), the mean age at diagnosis was 16.5 years-old and the orbit was the most affected site (4 cases). Microscopically, most cases were classified as embryonal RMS (6 cases) and the Desmin/Myogenin/Myo-D1 immunohistochemical positivity was useful to confirm the diagnosis. Chemotherapy and radiotherapy were applied to 9 and 8 patients respectively, whereas 2 patients were treated by surgery. Recurrences occurred in 3 patients and distant metastasis in 2 cases. Nine patients were alive in their last follow-up, 3 of them with disease, whereas 1 patient died due to the disease. Conclusions Head and neck RMS is an aggressive malignant neoplasm which demands especial concern to achieve early diagnosis and successful treatment.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofMedicina Oral Patologia Oral y Cirugia Bucalpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectrevista Medicina oral patologia oral y cirugia bucalpt_BR
dc.subjectfao clinica assunto rabdomiossarcoma busca dia 19 do 09 ano 2023 acesso open pmc key word: Rhabdomyosarcoma, soft tissue tumors, head and neck, oral cavity, chemotherapy .título:pt_BR
dc.subject.otherRhabdomyosarcomapt_BR
dc.subject.otherHeadpt_BR
dc.subject.otherNeckpt_BR
dc.subject.otherMouthpt_BR
dc.subject.otherDrug therapypt_BR
dc.subject.otherNeoplasmspt_BR
dc.subject.otherMedical recordspt_BR
dc.titleClinicopathological analysis of head and neck rhabdomyosarcoma: a series of 10 cases and literature reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911360/pt_BR
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