Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/60673
Tipo: Artigo de Periódico
Título: A Fully Adapted Headstage With Custom Electrode Arrays Designed for Electrophysiological Experiments
Autor(es): Flávio Afonso Gonçalves Mourão
Leonardo de Oliveira Guarnieri
Paulo Aparecido Amaral Júnior
Vinícius Rezende Carvalho
Eduardo Mazoni Andrade Marçal Mendes
Marcio Flavio Dutra Moraes
Resumo: Electrophysiological recordings lead amongst the techniques that aim to investigate the dynamics of neural activity sampled from large neural ensembles. However, the financial costs associated with the state-of-the-art technology used to manufacture probes and multi-channel recording systems make these experiments virtually inaccessible to small laboratories, especially if located in developing countries. Here, we describe a new method for implanting several tungsten electrode arrays, widely distributed over the brain. Moreover, we designed a headstage system, using the Intan® RHD2000 chipset, associated with a connector (replacing the expensive commercial Omnetics connector), that allows the usage of disposable and inexpensive cranial implants. Our results showed high-quality multichannel recording in freely moving animals (detecting local field, evoked responses and unit activities) and robust mechanical connections ensuring long-term continuous recordings. Our project represents an open source and inexpensive alternative to develop customized extracellular records from multiple brain regions.
Assunto: Laboratórios
Eletrodos
Tungstenio
Idioma: eng
País: Brasil
Editor: Universidade Federal de Minas Gerais
Sigla da Instituição: UFMG
Departamento: ENG - DEPARTAMENTO DE ENGENHARIA ELETRÔNICA
ENGENHARIA - ESCOLA DE ENGENHARIA
ICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICA
Tipo de Acesso: Acesso Aberto
Identificador DOI: https://doi.org/10.3389/fnins.2021.691788
URI: http://hdl.handle.net/1843/60673
Data do documento: 3-Mar-2022
metadata.dc.url.externa: https://www.frontiersin.org/articles/10.3389/fnins.2021.691788/full
metadata.dc.relation.ispartof: Frontiers in Neuroscience
Aparece nas coleções:Artigo de Periódico

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