Association of nitric oxide with oral lichen planus

Abdul Wahab  Alamir; Gururaj Arakeri; Shankargouda Patil; Kamran Habib Awan; Omar Kujan; Abdulsalam Aljabab; Felipe Paiva Fonseca; Peter  Brennan

Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60821

Full metadata record

DC Field	Value	Language
dc.creator	Abdul Wahab Alamir	pt_BR
dc.creator	Gururaj Arakeri	pt_BR
dc.creator	Shankargouda Patil	pt_BR
dc.creator	Kamran Habib Awan	pt_BR
dc.creator	Omar Kujan	pt_BR
dc.creator	Abdulsalam Aljabab	pt_BR
dc.creator	Felipe Paiva Fonseca	pt_BR
dc.creator	Peter Brennan	pt_BR
dc.date.accessioned	2023-11-10T21:20:25Z	-
dc.date.available	2023-11-10T21:20:25Z	-
dc.date.issued	2019	-
dc.citation.volume	48	pt_BR
dc.citation.issue	5	pt_BR
dc.citation.spage	345	pt_BR
dc.citation.epage	350	pt_BR
dc.identifier.doi	https://doi.org/10.1111/jop.12837	pt_BR
dc.identifier.issn	09042512	pt_BR
dc.identifier.uri	http://hdl.handle.net/1843/60821	-
dc.description.resumo	Background: The small signalling molecule nitric oxide (NO) has been postulated to have a mediator role in the pathogenesis of several diseases including oral lichen planus (OLP). This systematic review aimed to quantify the existing literature and assess the association of NO and OLP. Methods: The focused question being addressed was "Is there an association between nitric oxide and OLP?" PubMed, EMBASE, Scopus, and Web of Science, and grey literature from January 1990 to August 2018 were searched. Two independent reviewers performed the study selection using specified eligibility criteria. Results: Seven studies that met the eligibility criteria were included. All of these were case-control studies and 151 patients with OLP were evaluated (mostly females), with an age ranged from 20 to 75 years. The included studies showed a significant higher NO levels in OLP patients compared to the healthy controls, with two studies demonstrated a higher NO levels in erosive OLP compared to non-erosive OLP. Conclusion: These findings support that an association exists between higher NO concentration and OLP. However, larger high-quality studies with refined methodological design are needed to confirm the role of NO in the aetiology and pathogenesis of OLP	pt_BR
dc.language	eng	pt_BR
dc.publisher	Universidade Federal de Minas Gerais	pt_BR
dc.publisher.country	Brasil	pt_BR
dc.publisher.department	FAO - DEPARTAMENTO DE CLÍNICA	pt_BR
dc.publisher.initials	UFMG	pt_BR
dc.relation.ispartof	Journal of Oral Pathology & Medicine	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.subject.other	Biomarkers	pt_BR
dc.subject.other	Nitric oxide	pt_BR
dc.subject.other	Lichen planus, oral	pt_BR
dc.subject.other	Systematic review	pt_BR
dc.subject.other	Association	pt_BR
dc.title	Association of nitric oxide with oral lichen planus	pt_BR
dc.type	Artigo de Periódico	pt_BR
dc.url.externa	https://onlinelibrary.wiley.com/doi/10.1111/jop.12837	pt_BR
Appears in Collections:	Artigo de Periódico

Files in This Item:

There are no files associated with this item.

Show simple item record