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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60890
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dc.creatorRaquel de Oliveirameirapt_BR
dc.creatorDaniel Nogueira Mendes Bragapt_BR
dc.creatorLeni Safira Gonçalves Pinheiropt_BR
dc.creatorIzabela Ferreira Gontijo Amorimpt_BR
dc.creatorLeonardo de Souza Vasconcellospt_BR
dc.creatorLuiz Ronaldo Albertipt_BR
dc.date.accessioned2023-11-13T19:45:41Z-
dc.date.available2023-11-13T19:45:41Z-
dc.date.issued2020-
dc.citation.volume35pt_BR
dc.citation.issue10pt_BR
dc.citation.spage1pt_BR
dc.citation.epage11pt_BR
dc.identifier.doi10.1590/s0102-865020200100000006pt_BR
dc.identifier.issn16782674pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60890-
dc.description.resumoPurpose: To evaluate and compare the effects of homologous and heterologous PRP (Platelet-Rich Plasma) on the quality and speed of skin wound healing, compared to Poor Platelet Plasma (PPP).Methods: Twenty-one male adult rabbits were used; two for preparing homologous PRP, with the rest of them separated randomly in three groups, according to the treatment received: PPP – control (n=5), homologous PRP (n=7), heterologous (n=7). Excisional skin wounds were made on the back of the animals, for the application of homologous and heterologous PPP and PRP. At the 14th post-operative day (POD), the animals were subjected to a new wound, and the treatments were inverted. The wounds were evaluated macroscopically and histologically.Results: A larger percentage of scar retraction was observed on the group treated with heterologous PRP, compared to homologous PRP, at the third POD, an increase of 25.03% (p=0.01). No other statistically significant differences among treatments were observed. Among every group, skin healing was efficient, without local adverse effects.Conclusions: Heterologous PRP contributed with more tissue retraction at the beginning of the wound healing process. After this, there were no differences on the wound healing skin process treated with PRP or PPP. However, our findings suggest the presence of others plasmatic factors, besides platelets,which could also contribute to the wound healing process, and thus, should be further investigated.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTARpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofActa Cirúrgica Brasileira-
dc.rightsAcesso Abertopt_BR
dc.subjectPlatelet-Rich Plasmapt_BR
dc.subjectWound Healingpt_BR
dc.subjectRabbitspt_BR
dc.subject.otherPlatelet-Rich Plasmapt_BR
dc.subject.otherRabbitspt_BR
dc.subject.otherWound Healingpt_BR
dc.titleEffects of homologous and heterologous rich platelets plasma, compared to poor platelets plasma, on cutaneous healing of rabbitspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/s0102-865020200100000006pt_BR
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