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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61286
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dc.creatorHenrique de Assis Fonseca Tonellipt_BR
dc.creatorZilda Maria Alves Meirapt_BR
dc.creatorSandra Regina Tolentino Castilhopt_BR
dc.creatorAdriana Furletti Machado Guimarãespt_BR
dc.creatorTháis Costa Nascentes Queirozpt_BR
dc.creatorAlexandre Rodrigues Ferreirapt_BR
dc.date.accessioned2023-11-22T21:24:50Z-
dc.date.available2023-11-22T21:24:50Z-
dc.date.issued2022-02-
dc.citation.volume35pt_BR
dc.citation.issue5pt_BR
dc.citation.spage657pt_BR
dc.citation.epage664pt_BR
dc.identifier.doihttps://doi.org/10.36660/ijcs.20210207pt_BR
dc.identifier.issn2359-5647pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61286-
dc.description.resumoBackground: Left isomerism (LI) is a common finding in patients with biliary atresia (BA), and it can be identified by echocardiography. Several comorbidities may be present in patients with LI, including heart disease. Objective: To investigate the prevalence of LI and heart disease in children (< 18 years of age) with BA followed-up at Hospital das Clínicas, UFMG. Methods: This is a cross-sectional study involving patients diagnosed with BA between February 2016 and April 2020 who underwent transthoracic echocardiography and, in case of situs abnormalities, also electrocardiography. Results: Our study recruited 58 patients (mean age: 3.08 years; female/male ratio: 1.5:1). The general prevalence of situs abnormalities was 8.6% (5/58) and the most common one was LI (4/5 or 80%). One patient had situs inversus. Among patients with situs abnormalities, the general prevalence of heart disease was 80% (4/5), apart from anomalies of the inferior vena cava), with pulmonary valve stenosis (PVS) as the only change seen (75% of mild forms and 25% of moderate forms). Among patients with situs abnormalities, the prevalence of rhythm changes was 80% (4/5), and low atrial rhythm was the most common finding (3/4 or 75%). Conclusion: The prevalence of situs abnormalities in our sample was similar to that described in the literature. We observed an exclusive prevalence of PVS and a high prevalence of rhythm changes among patients with LI. Although the diagnosis of isomerism does not initially add much cardiovascular risk to the sample, possible late deterioration should be considered.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Cardiovascular Sciences (online)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectHeterotaxy Syndromept_BR
dc.subjectHeart diseasespt_BR
dc.subjectBiliary atresiapt_BR
dc.subject.otherCardiopatiaspt_BR
dc.subject.otherAtresia biliarpt_BR
dc.titleAbnormalities of cardiac situs and heart disease diagnosed by echocardiography in patients with biliary atresiapt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://ijcscardiol.org/article/abnormalities-of-cardiac-situs-and-heart-disease-diagnosed-by-echocardiography-in-patients-with-biliary-atresia/pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4610-6439pt_BR
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