Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/61292
Type: | Artigo de Periódico |
Title: | Immunology and immunopathogenesis of human leishmaniasis |
Authors: | Juliana P. B. de Menezes Cláudia Brodskyn Ricardo Gonçalves Olivia Bacellar |
Abstract: | Leishmaniasis is a disease that affects people and animals worldwide and can be broadly divided into visceral (VL) and tegumentary (TL) forms. TL caused by Leishmania braziliensis presents a wide spectrum de clinical manifestations ranging from a single and typical ulcer known as CL to the involvement of nasal or oral mucosal, mucosal leishmaniasis (ML). Between both clinical forms, there is diffuse cutaneous leishmaniasis (DCL) caused by Leishmania amazonensis. This spectrum included atypical cutaneous leishmaniasis (ACL) characterized by vegetative, verrucous, crusted and lupoid lesions (Guimarães et al., 2016). Human VL is characterized by depressed cell-mediated immunity and decreased Th1 immune response (Carvalho et al., 1989; Bacellar et al., 2000). Also, VL is associated with increased production of multiple pro-inflammatory cytokines and chemokines (Saporito et al., 2013; Palacios et al., 2021; Tasew et al., 2021). |
Subject: | Leishmania Pioglitazona Patogênese Homeopática |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | ICB - DEPARTAMENTO DE PATOLOGIA ICB - INSTITUTO DE CIÊNCIAS BIOLOGICAS |
Rights: | Acesso Aberto |
metadata.dc.identifier.doi: | https://doi.org/10.3389/fcimb.2022.1055221 |
URI: | http://hdl.handle.net/1843/61292 |
Issue Date: | 2022 |
metadata.dc.url.externa: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.1055221/full |
metadata.dc.relation.ispartof: | Frontiers in Cellular and Infection Microbiology |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Editorial_ Immunology and immunopathogenesis of human leishmaniasis.pdf | 154.11 kB | Adobe PDF | View/Open |
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