Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61800
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dc.creatorIlaria Testipt_BR
dc.creatorCarl Herbortpt_BR
dc.creatorLuca Ciminopt_BR
dc.creatorSalam Iriqatpt_BR
dc.creatorJennifer e. Thornept_BR
dc.creatorJose Echegaraypt_BR
dc.creatorKalpana Babupt_BR
dc.creatorAlexander Arthur Bialasiewiczpt_BR
dc.creatorDebra a. Goldsteinpt_BR
dc.creatorNima Ghadiript_BR
dc.creatorAlex Fonollosa Calduchpt_BR
dc.creatorCamilo Brandão-de-resendept_BR
dc.creatorGabriel Costa de Andradept_BR
dc.creatorPadmamalini Mahendradaspt_BR
dc.creatorJulio j. González-lópezpt_BR
dc.creatorEster Carreñopt_BR
dc.creatorRola n. Hamampt_BR
dc.creatorNicole Stübigerpt_BR
dc.creatorBahram Bodaghipt_BR
dc.creatorYu-jang Chaopt_BR
dc.creatorMasaru Takeuchipt_BR
dc.creatorMei-ling Tay-kearneypt_BR
dc.creatorRupesh Agrawalpt_BR
dc.creatorAlejandro Porteropt_BR
dc.creatorHiroshi Keinopt_BR
dc.creatorMar Esteban-ortegapt_BR
dc.creatorJoanna Prze'dziecka-do'ykpt_BR
dc.creatorAleksandra Radosavljevi'pt_BR
dc.creatorIan Paredespt_BR
dc.creatorho su Lingpt_BR
dc.creatorWei Kiongpt_BR
dc.creatorMelissa Tienpt_BR
dc.creatorCarlos Pavesiopt_BR
dc.creatorXin le ngpt_BR
dc.creatorSoon Phaik Cheept_BR
dc.creatorJay Siakpt_BR
dc.creatorInes Hernanz-rodriguezpt_BR
dc.creatorVictor Menezopt_BR
dc.creatorChristoph Tappeinerpt_BR
dc.creatorFranz Marie Cruzpt_BR
dc.creatorPeter Addisonpt_BR
dc.creatorLaura Steeplespt_BR
dc.creatorRobert Kuijperspt_BR
dc.creatorDaniel Vítor de Vasconcelos Santospt_BR
dc.creatorBalini Balasubramaniampt_BR
dc.creatorPeter Mccluskeypt_BR
dc.creatorFrancesco Pichipt_BR
dc.creatorAniruddha Agarwalpt_BR
dc.date.accessioned2023-12-06T19:27:15Z-
dc.date.available2023-12-06T19:27:15Z-
dc.date.issued2022-
dc.citation.volume12pt_BR
dc.citation.issue4pt_BR
dc.citation.spage1pt_BR
dc.citation.epage6pt_BR
dc.identifier.doihttps://doi.org/10.1186/s12348-021-00275-xpt_BR
dc.identifier.issn1869-5760pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61800-
dc.description.resumoBackground Inflammatory adverse events following COVID-19 vaccination are being reported amidst the growing concerns regarding vaccine’s immunogenicity and safety, especially in patients with pre-existing inflammatory conditions. Methods Multinational case series of patients diagnosed with an ocular inflammatory event within 14 days following COVID-19 vaccination collected from 40 centres over a 3 month period in 2021. Results Seventy patients presented with ocular inflammatory events within 14 days following COVID-19 vaccination. The mean age was 51 years (range, 19–84 years). The most common events were anterior uveitis (n = 41, 58.6%), followed by posterior uveitis (n = 9, 12.9%) and scleritis (n = 7, 10.0%). The mean time to event was 5 days and 6 days (range, 1–14 days) after the first and second dose of vaccine, respectively. Among all patients, 36 (54.1%) had a previous history of ocular inflammatory event. Most patients (n = 48, 68.6%) were managed with topical corticosteroids. Final vision was not affected in 65 (92.9%), whereas 2 (2.9%) and 3 (4.3%) had reduction in visual acuity reduced by ≤3 lines and > 3 lines, respectively. Reported complications included nummular corneal lesions (n = 1, 1.4%), cystoid macular oedema (n = 2, 2.9%) and macular scarring (n = 2, 2.9%). Conclusion Ocular inflammatory events may occur after COVID-19 vaccination. The findings are based on a temporal association that does not prove causality. Even in the possibility of a causal association, most of the events were mild and had a good visual outcome.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIApt_BR
dc.publisher.departmentMEDICINA - FACULDADE DE MEDICINApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Ophthalmic Inflammation and Infectionpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectUveitispt_BR
dc.subjectOcular inflammationpt_BR
dc.subjectImmunomodulatorypt_BR
dc.subjectCoronavirus diseasept_BR
dc.subjectCOVID-19pt_BR
dc.subjectSARS-CoV-2pt_BR
dc.subjectVaccinationpt_BR
dc.subject.otherCOVID-19pt_BR
dc.subject.otherVacinaçãopt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.subject.otherInflamaçãopt_BR
dc.subject.otherUveítept_BR
dc.titleOcular inflammatory events following COVID-19 vaccination: a multinational case seriespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://joii-journal.springeropen.com/articles/10.1186/s12348-021-00275-xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6747-2024pt_BR
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