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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61805
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dc.creatorAna Paula Camargos de Figueirêdo Nevespt_BR
dc.creatorCecilia Gómez Ravettipt_BR
dc.creatorVandack Nobrept_BR
dc.creatorAngélica Gomides dos Reis Gomespt_BR
dc.creatorPaula Frizera Vassallopt_BR
dc.creatorAna Cristina Simões e Silvapt_BR
dc.creatorFrancisco Guilherme Cancela e Pennapt_BR
dc.creatorFabrício de Lima Bastospt_BR
dc.creatorMateus Rocha Munizpt_BR
dc.creatorGuilherme Carvalho Rochapt_BR
dc.creatorAugusto Cesar Soares Dos Santos Júniorpt_BR
dc.date.accessioned2023-12-06T19:29:12Z-
dc.date.available2023-12-06T19:29:12Z-
dc.date.issued2022-08-08-
dc.citation.volume140pt_BR
dc.citation.issue4pt_BR
dc.citation.spage559pt_BR
dc.citation.epage565pt_BR
dc.identifier.doihttps://doi.org/10.1590/1516-3180.2021.0641.r2.12112021pt_BR
dc.identifier.issn1806-9460pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61805-
dc.description.resumoBACKGROUND: Acute kidney injury (AKI) is a frequent complication during the postoperative period following liver transplantation. Occurrence of AKI in intensive care unit (ICU) patients is associated with increased mortality and higher costs. OBJECTIVE: To evaluate occurrences of moderate or severe AKI among patients admitted to the ICU after liver transplantation and investigate characteristics associated with this complication. DESIGN AND SETTING: Single-center retrospective cohort study in a public hospital, Belo Horizonte, Brazil. METHODS: Forty-nine patients admitted to the ICU between January 2015 and April 2017 were included. AKI was defined from a modified Kidney Disease Improving Global Outcomes (KDIGO) score (i.e. based exclusively on serum creatinine levels). RESULTS: Eighteen patients (36.7%) developed AKI KDIGO 2 or 3; mostly KDIGO 3 (16 out of the 18 patients). Lactate level within the first six hours after ICU admission (odds ratio, OR: 1.3; 95% confidence interval, CI: 1.021-1.717; P = 0.034) and blood transfusion requirement within the first week following transplantation (OR: 8.4; 95% CI: 1.687-41.824; P = 0.009) were independently associated with development of AKI. Patients with AKI KDIGO 2 or 3 underwent more renal replacement therapy (72.2% versus 3.2%; P < 0.01), had longer hospital stay (20 days versus 15 days; P = 0.001), higher in-hospital mortality (44.4% versus 6.5%; P < 0.01) and higher mortality rate after one year (44.4% versus 9.7%; P = 0.01). CONCLUSION: Need for blood transfusion during ICU stay and hyperlactatemia within the first six postoperative hours after liver transplantation are independently associated with moderate or severe AKI. Developing AKI is apparently associated with poor outcomes.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofSao Paulo Medical Journalpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAcute renal injurypt_BR
dc.subjectAcute kidney injurypt_BR
dc.subjectLiver transplantationpt_BR
dc.subjectClinical outcomept_BR
dc.subjectPostoperativept_BR
dc.subjectCritically ill patientspt_BR
dc.subject.otherUnidades de Terapia Intensivapt_BR
dc.subject.otherFatores de riscopt_BR
dc.subject.otherMortalidadept_BR
dc.titleRisk factors for acute kidney injury after liver transplantation in intensive care unit: a retrospective cohort studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.scielo.br/j/spmj/a/85gnScq7vnPT6cpY3PkXSYC/?lang=enpt_BR
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