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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61828
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dc.creatorVívian Mara Gonçalves de Oliveira Azevedopt_BR
dc.creatorClaudia Regina Lindgren Alvespt_BR
dc.creatorGabriela Soutto Mayor Assumpção Pinheiropt_BR
dc.creatorAline Almeida Bentespt_BR
dc.creatorGabriela Cintra Januáriopt_BR
dc.creatorJosé Nélio Januáriopt_BR
dc.creatorMila Lemos Cintrapt_BR
dc.creatorAna Beatriz Araújo de Souzapt_BR
dc.creatorLaura Gregório Pirespt_BR
dc.creatorStela Maris Aguiar Lemospt_BR
dc.date.accessioned2023-12-06T23:42:45Z-
dc.date.available2023-12-06T23:42:45Z-
dc.date.issued2022-
dc.citation.volume38pt_BR
dc.citation.issue8pt_BR
dc.citation.spage1pt_BR
dc.citation.epage8pt_BR
dc.identifier.doi10.1590/0102-311XEN021022pt_BR
dc.identifier.issn16784464pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61828-
dc.description.resumoThis serological survey, conducted in five Brazilian municipalities, evaluated the use of dried blood spots (DBS), obtained from newborns and their mothers, to detect SARS-CoV-2 IgG antibodies. DBS were obtained from 4,803 neonates aged up to seven days and their mothers, both asymptomatic, at public health care clinics during newborn screening. DBS were processed by ELISA to detect IgG antibodies against SARS-CoV-2 nucleocapsid antigen. Mothers of seropositive neonates were interviewed about sociodemographic char acteristics and clinical and laboratory antecedents. Non-satisfactory samples, dyads with incomplete data, and vaccinated mothers were excluded. Of the 1,917 DBS dyads samples analyzed, 14.7% of neonates showed IgG antibodies against SARS-CoV-2. Among seropositive neonates, 73.2% of their mothers were also seropositive. More than half of the mothers with seropositive neonates denied clinical or laboratory suspicion of COVID-19 during pregnancy. Suspicion occurred in the third trimester for 24.6% of the mothers. This study tested an innovative strategy to improve the understanding of COVID-19 antibody dynamics during pregnancy and suggests the feasibility of a universal serological survey in puerperal women and neonates.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE FONOAUDIOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofCadernos de Saúde Pública-
dc.rightsAcesso Abertopt_BR
dc.subjectSARS-CoV-2pt_BR
dc.subjectNewbornpt_BR
dc.subjectPregnancypt_BR
dc.subjectNeonatal Screeningpt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.subject.otherNewbornpt_BR
dc.subject.otherPregnancypt_BR
dc.subject.otherNeonatal Screeningpt_BR
dc.titleSerological survey for igg antibodies against sars-cov-2 through newborn screeningpt_BR
dc.title.alternativeInquérito sorológico para anticorpos IgG contra SARS-CoV-2 de recém-nascidos e suas mãespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/0102-311XEN021022pt_BR
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