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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61864
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dc.creatorJanaina Ribeiro Oliveirapt_BR
dc.creatorSérgio Henrique Sousa Santospt_BR
dc.creatorJoão Marcus Oliveira Andradept_BR
dc.creatorDeborah Farias Lelispt_BR
dc.creatorAlanna Fernandes Paraisopt_BR
dc.creatorAlfredo Mauricio Batista de Paulapt_BR
dc.creatorAndre Luiz Sena Guimarãespt_BR
dc.creatorJuliana Pinto de Limapt_BR
dc.creatorJunio Cota Silvapt_BR
dc.creatorDiego Vicente Costapt_BR
dc.date.accessioned2023-12-08T17:45:45Z-
dc.date.available2023-12-08T17:45:45Z-
dc.date.issued2023-
dc.citation.volume9pt_BR
dc.citation.issue2pt_BR
dc.identifier.issn2352-4588pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61864-
dc.description.resumoThe edible insect dietary supplementation option for nutritional disturbances is a promising scientific investigation field, especially in the obesity context. The aim of the present study was to evaluated the Madagascar cockroach (Gromphadorhina portentosa) flour (CF) influence on the body composition, biochemical profile and inflammatory markers in obese mice liver. Mice were divided in four groups: Control AIN-93, AIN-93+Madagascar cockroach flour (AIN93+CF), high-fat diet (HFD) and HFD+Madagascar cockroach flour (HFD+CF). The groups were treated for eight weeks (4 weeks of obesity induction + 4 weeks supplemented with CF isocaloric diet). Body composition, biochemical levels and molecular markers were evaluated. The main results showed a decreased fasting glucose, total cholesterol, triglycerides, and pyruvic transaminase/aspartate aminotransferase in the HFD-CF treated animals compared to HFD. Moreover, it was observed a decreased liver interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α) inflammatory markers expression in HFD+CF mice. These data reveal that Madagascar cockroach flour may be a useful dietary supplement to improve biochemical and inflammatory obesity alterations.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Insects as Food and Feed-
dc.rightsAcesso Restritopt_BR
dc.subjectInsectpt_BR
dc.subjectBug proteinpt_BR
dc.subjectFatpt_BR
dc.subjectHepatic diseasespt_BR
dc.subjectInflammationpt_BR
dc.subjectSteatosispt_BR
dc.subject.otherInsetos comestíveispt_BR
dc.subject.otherFigado - Insuficiênciapt_BR
dc.subject.otherObesidadept_BR
dc.titleDietary supplementation with Madagascar cockroach (Gromphadorhina portentosa) flour improves metabolic parameters reducing hepatic inflammatory markers in obese micept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.3920/JIFF2022.0043pt_BR
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